The concept of aggressive nutrition therapy and clinical indication: A position paper

Nishioka, Shinta; Nakahara, S.; Miyuki, Takasaki; Shiohama, Nahoko; Kokura, Yoji; Suzuki, Tatsuro; Yokoi-Yoshimura, Yuri; Nii, Maria; Maeda, Keisuke; Wakabayashi, Hidetaka

doi:10.1016/j.clnesp.2022.09.013

Cited by 8 publications

(11 citation statements)

References 63 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Rehabilitation pharmacotherapy induces the highest functions and QOL by both rehabilitation and pharmacotherapy including anamorelin and Kampo medicines 25 . Diagnostic reasoning including nutritional status, sarcopenia, excess and/or insufficient nutrient intake, cachexia 26▪ , SMART (Specific, Measurable, Achievable, Realistic/Relevant, and Timed) goal setting 27 , and aggressive nutrition therapy to improve nutritional status 28 are important steps in rehabilitation nutrition care process. Enhanced nutritional care for cancer patients undergoing (or after) anticancer treatment and rehabilitation is weakly recommended in the updated clinical practice guidelines for rehabilitation nutrition 29 .…”

Section: Rehabilitation Nutrition and Rehabilitation Pharmacotherapy ...mentioning

confidence: 99%

Anamorelin in Japanese patients with cancer cachexia: an update

Wakabayashi

Arai

Inui

2023

Current Opinion in Supportive &Amp; Palliative Care

Self Cite

View full text Add to dashboard Cite

Purpose of review Anamorelin was approved for production and marketing in Japan on 22 January 2021 for cancer cachexia in non-small-cell lung cancer, gastric cancer, pancreatic cancer, and colorectal cancer. The authors describe the updates of anamorelin for cancer cachexia in Japan. Recent findings Recent evidence showed that anamorelin improved lean body mass, body weight, and appetite in patients with cancer cachexia in clinical practice. Anamorelin does not increase body weight in the severe-weight-loss group in cachectic patients with pancreatic cancer. Several case reports showed that anamorelin can cause cardiac adverse drug reactions. Among the cardiac adverse reactions, fatal arrhythmias should be monitored carefully even if it is the first dose. Anamorelin combined with nutrition, physical activity, and exercise may be more useful than anamorelin alone for treating cancer cachexia. An interim analysis from post-marketing all-case surveillance was performed; however, details have not yet been published. When anamorelin cannot be used for cancer cachexia, Kampo medicines can be considered as an option. Summary Anamorelin has changed the clinical practice of cancer cachexia in Japan. The authors hope that anamorelin is available for other disease-related cachexia along with appropriate multidisciplinary interventions.

show abstract

Section: Rehabilitation Nutrition and Rehabilitation Pharmacotherapy ...mentioning

confidence: 99%

Anamorelin in Japanese patients with cancer cachexia: an update

Wakabayashi

Arai

Inui

2023

Current Opinion in Supportive &Amp; Palliative Care

Self Cite

View full text Add to dashboard Cite

show abstract

“…Rehabilitation is defined as a set of interventions designed to optimize functioning and reduce disability in individuals in interaction with their environment. The Japanese Association of Rehabilitation Nutrition has published position papers on goal setting for nutrition and body weight in rehabilitation nutrition 5 and the concept of aggressive nutrition therapy 6 to improve both nutritional status and function more.…”

Section: Geriatricsmentioning

confidence: 99%

“…Subjective well-being was assessed using the five-item World Health Organization Well-Being Index (WHO-5), measuring positive mental health status in the past 2 weeks (0-25 points; higher scores indicate greater well-being). 5,6 Five aspects of attitudes toward beauty and personal grooming were evaluated based on a previous survey 7 : (1) careful grooming regardless of age, (2) careful grooming when meeting others, (3) careful grooming when going out, (4) finding beauty and grooming enjoyable, and (5) trying new beauty and fashion. The responses on each item were divided into "yes" ("agree" or "somewhat agree") and "no" ("disagree" or "somewhat disagree").…”

Section: Geriatricsmentioning

confidence: 99%

Triad of rehabilitation, nutrition, and oral management for sarcopenic dysphagia in older people

Wakabayashi

2023

Geriatrics Gerontology Int

Self Cite

View full text Add to dashboard Cite

show abstract

“…Aggressive nutrition therapy is nutritional care management that sets goals for total daily energy intake according to daily energy expenditure and daily energy accumulation [ 35 ]. Older patients require more than 250 kcal/day of daily energy accumulation to gain 1 kg of body weight per month [ 65 ]. A mean provided energy intake of ≥30 kcal/ideal body weight (kg)/day improved swallowing function in older patients with dysphagia, and ADL improved significantly in the patient undergoing rehabilitation in the acute care hospital [ 66 ].…”

Section: Sarcopenic Dysphagiamentioning

confidence: 99%

Sarcopenic Dysphagia and Simplified Rehabilitation Nutrition Care Process: An Update

Kakehi,

Isono,

Wakabayashi

et al. 2023

Ann Rehabil Med

Self Cite

View full text Add to dashboard Cite

Sarcopenic dysphagia is characterized by weakness of swallowing-related muscles associated with whole-body sarcopenia. As the number of patients with sarcopenia increases with the aging of the world, the number of patients with sarcopenic dysphagia is also increasing. The prevalence of sarcopenic dysphagia is high in the institutionalized older people and in patients hospitalized for pneumonia with dysphagia in acute care hospitals. Prevention, early detection and intervention of sarcopenic dysphagia with rehabilitation nutrition are essential. The diagnosis of sarcopenic dysphagia is based on skeletal and swallowing muscle strength and muscle mass. A reliable and validated diagnostic algorithm for sarcopenic dysphagia is used. Sarcopenic dysphagia is associated with malnutrition, which leads to mortality and Activities of Daily Living (ADL) decline. The rehabilitation nutrition approach improves swallowing function, nutrition status, and ADL. A combination of aggressive nutrition therapy to improve nutrition status, dysphagia rehabilitation, physical therapy, and other interventions can be effective for sarcopenic dysphagia. The rehabilitation nutrition care process is used to assess and problem solve the patient’s pathology, sarcopenia, and nutrition status. The simplified rehabilitation nutrition care process consists of a nutrition cycle and a rehabilitation cycle, each with five steps: assessment, diagnosis, goal setting, intervention, and monitoring. Nutrition professionals and teams implement the nutrition cycle. Rehabilitation professionals and teams implement the rehabilitation cycle. Both cycles should be done simultaneously. The nutrition diagnosis of undernutrition, overnutrition/obesity, sarcopenia, and goal setting of rehabilitation and body weight are implemented collaboratively.

show abstract

The concept of aggressive nutrition therapy and clinical indication: A position paper

Cited by 8 publications

References 63 publications

Anamorelin in Japanese patients with cancer cachexia: an update

Anamorelin in Japanese patients with cancer cachexia: an update

Triad of rehabilitation, nutrition, and oral management for sarcopenic dysphagia in older people

Sarcopenic Dysphagia and Simplified Rehabilitation Nutrition Care Process: An Update

Contact Info

Product

Resources

About