In order to improve the productivity of lactating cows and preserve their health, scientists and practitioners are searching for complex feed additives that have valuable biological properties. An experiment aimed to study the effect of feeding coniferous flour, pine nutshell, arabinogalactan, and enzyme preparation Amilosubtilin G3x on the biochemical and hematological parameters was conducted in the LLC “Plemzavod “Taezhny” of the Krasnoyarsk region. According to the principle of analogs, three groups of dairy black-motley cows including 15 animals were formed. The experiment lasted 100 days. The diet for cows of the control group was basic, experimental group 1 was fed with coniferous flour (50 g / goal / day), cedar nutshell (50 g / goal / day), Amilosubtilin G3x (5 g / goal / day), cows of experimental group 2 were fed with coniferous flour (50 g / goal / day), pine nutshell (50 g / goal / day), Amilosubtilin G3x (5 g / goal / day), and arabinogalactan (5 g / goal / day). It was found that the additives did not have a negative effect on the metabolism, but improved blood counts. In the blood of experimental group 2, the concentration of total protein was higher by 2.7% and 2.0%, albumin by 3.0 and 1.0%, calcium by 1, 5 and 6.3%, phosphorus by 10.2 and 10.7%, creatinine by 6.0 and 16.5%, glucose by 4.0 and 2.8%, triglycerides by 11.1% in comparison with the control group and experimental group 1, respectively. The results obtained indicate that the additives can be used for feeding cows.