2021
DOI: 10.1038/s41598-021-01370-8
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The condition of the oral cavity at the time of diagnosis of inflammatory bowel disease in pediatric patients

Abstract: Changes in the oral mucosa can appear in the course of inflammatory bowel disease in both children and adults. They often precede the appearance of gastrointestinal symptoms. The aim of the study was to determine the nature of changes in the oral cavity at the time of diagnosis of inflammatory bowel disease in children compared to children without systemic diseases. 49 children diagnosed with inflammatory bowel disease and 60 children without systemic diseases were examined. The prevalence of the aphthae stoma… Show more

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Cited by 4 publications
(5 citation statements)
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“…Moreover, inflammatory bowel disease is increasingly being recognized as a complex multifactorial and multisystemic disorder [6]. Alarmingly high rates of depression within the adolescent IBD population have been observed in the largest population-based study, which aimed to evaluate the burden of psychiatric disorders in children and young adults with IBD in USA, comprising a total of 11,316,450 patients aged between 5 and 24 years, including 58.020 patients with a diagnosis of IBD. The prevalence of psychiatric disorders was found to be 21.6% among IBD, and mainly comprised depression and anxiety disorders.…”
Section: Psychological Implications In Inflammatory Bowel Disease 21 ...mentioning
confidence: 99%
“…Moreover, inflammatory bowel disease is increasingly being recognized as a complex multifactorial and multisystemic disorder [6]. Alarmingly high rates of depression within the adolescent IBD population have been observed in the largest population-based study, which aimed to evaluate the burden of psychiatric disorders in children and young adults with IBD in USA, comprising a total of 11,316,450 patients aged between 5 and 24 years, including 58.020 patients with a diagnosis of IBD. The prevalence of psychiatric disorders was found to be 21.6% among IBD, and mainly comprised depression and anxiety disorders.…”
Section: Psychological Implications In Inflammatory Bowel Disease 21 ...mentioning
confidence: 99%
“…Among the most valuable cardiospecific markers recommended for diagnosing myocardial infarction and cardiac failure, the determination of CTs and natriuretic peptides in urine has shown promising results. Recent studies by several research groups have shown the high diagnostic significance of CTs and natriuretic peptides in noninvasively obtained body fluids in individuals with coronary heart disease [46,95], myocardial infarction [43-45, 47, 96, 97], diabetes mellitus [45], cardiac failure [98,99] and HT [54]. Further research should be aimed at clarifying these promising diagnostic possibilities.…”
Section: Effect Of Bp On Glomerular Filtration Rate and Elimination O...mentioning
confidence: 99%
“…an unfavorable prognosis [38][39][40][41]; 4) Diagnostic significance of CTs concentrations in urine and oral fluid (saliva) in case of CVDs [42][43][44][45][46][47]. This new field of noninvasive diagnostics and monitoring of CVDs has promising prospects due to a number of advantages associated with obtaining biomaterial.…”
Section: Introduction: Biochemistry and Diagnostic Contribution Of Ca...mentioning
confidence: 99%
“…Klichowska-Palonka et al. reported that the incidence of AC in paediatric patients with UC is approximately 12.5% ( 56 ). Furthermore, Goldinova and colleagues found that 21.6% of patients with UC had AC, compared with none in the control group without UC ( 41 ).…”
Section: Introductionmentioning
confidence: 99%
“…Taken together, the manifestations of PSV, RAU, AG, BMS, AC, dry mouth, taste change, halitosis and periodontitis may serve as a clue to the diagnosis of UC ( 18 , 20 , 25 , 41 , 42 , 56 , 61 ); Among these, RAU and periodontitis might serve as a strong sign of latent UC through assessing these relevant studies using Grading of Recommendations Assessment, Development and Evaluation (GRADE) standard ( 69 ), and PSV, as a rare disease, may represent the relatively specific sign of UC to some extent ( Table 2 ). Therefore, when patients present with these oral manifestations, they should be screened for UC by enquiring specifically about potential UC-related gastrointestinal symptoms upon history-taking.…”
Section: Introductionmentioning
confidence: 99%