RSC Adv.
 2024
DOI: 10.1039/d4ra01683a
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The conjugates of 5′-deoxy-5-fluorocytidine and hydroxycinnamic acids – synthesis, anti-pancreatic cancer activity and molecular docking studies

Marcin Cybulski,
Magdalena Zaremba-Czogalla,
Bartosz Trzaskowski
et al.

Abstract: New conjugates 1–6 containing 5-dFCR and selected hydroxycinnamic acids were synthesized and tested in vitro against pancreatic cancer (PDAC) lines. The ADME properties and molecular docking to CES2 or human albumin were discussed.

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