The consequential impact of JUUL on youth vaping and the landscape of tobacco products: The state of play in the COVID-19 era

Besaratinia, Ahmad; Tommasi, Stefania

doi:10.1016/j.pmedr.2021.101374

Cited by 18 publications

(20 citation statements)

References 78 publications

(174 reference statements)

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“…This has led to the perception that e-cig use/vaping is safe or lessharmful than tobacco smoking [28,29]. Whilst the lower levels of toxicants and carcinogens in e-cig vapor may imply mitigated health risk, they cannot, however, equate to no risk [6]. In fact, exposure to many of the same constituents of e-cig vapor, at various concentrations, has been associated with a wide range of cardiovascular-, immune-related (inflammatory), and respiratory diseases, and cancer [22,[30][31][32][33][34].…”

Section: Health Consequences: Smoking Vs Vapingmentioning

confidence: 99%

“…Having the sole or major ownership of products responsible for both the global tobacco epidemic and youth vaping epidemic, Altria is facing various litigations [ 6 ]. On April 1, 2020, the Federal Trade Commission (FTC) filed an administrative complaint alleging that Altria Group Inc. and Juul Labs, Inc. entered a series of agreements, including a merger that turned Altria into JUUL's largest shareholder [ 13 ].…”

Section: Litigations Concerning Altria's Ownership Of Combustible and Electronic Cigarettesmentioning

confidence: 99%

“…Started in 2017, Juul Inc. is a spin off company from Pax Labs, which was a manufacturer of vaporizing devices for cannabis and loose-leaf tobacco; Pax Labs was preceded by Ploom as the original company for e-cig development [ 5 ]. Remarkably, JUUL's use of salt-based nicotine, which is significantly less aversive than freebase nicotine, made it very quickly popular among naïve users, particularly adolescents and youth [ 6 ]. The high content of nicotine in JUUL, which was claimed to be equivalent to nicotine content of a pack of 20 cigarettes, also made JUUL highly appealing to adult smokers, seeking a putatively less-harmful alternative to combustible cigarettes [ 6 ].…”

Section: A Historical Introductionmentioning

confidence: 99%

“…Remarkably, JUUL's use of salt-based nicotine, which is significantly less aversive than freebase nicotine, made it very quickly popular among naïve users, particularly adolescents and youth [ 6 ]. The high content of nicotine in JUUL, which was claimed to be equivalent to nicotine content of a pack of 20 cigarettes, also made JUUL highly appealing to adult smokers, seeking a putatively less-harmful alternative to combustible cigarettes [ 6 ]. Shortly after its launch, JUUL became the preeminent vaping product on the market and a dominant player in the vaping industry [ 5 , 6 ].…”

Section: A Historical Introductionmentioning

confidence: 99%

“…The high content of nicotine in JUUL, which was claimed to be equivalent to nicotine content of a pack of 20 cigarettes, also made JUUL highly appealing to adult smokers, seeking a putatively less-harmful alternative to combustible cigarettes [ 6 ]. Shortly after its launch, JUUL became the preeminent vaping product on the market and a dominant player in the vaping industry [ 5 , 6 ]. In December 2018, Altria, one of the world's largest cigarette manufacturers and the parent company of Philip Morris USA, acquired a 35% stake in JUUL [ 7 ].…”

Section: A Historical Introductionmentioning

confidence: 99%

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From Tobacco Cigarettes to Electronic Cigarettes: The Two Sides of a Nicotine Coin

Besaratinia

2021

Front. Oral. Health

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Tobacco smoking-related diseases, including cardiovascular disease, pulmonary disease, stroke, and cancer in multiple organ sites, are the leading causes of preventable death, worldwide. Youth electronic cigarette use (vaping) is an evolving public health problem in the United States and around the world. Many of the same toxicants and carcinogens present in tobacco smoke are also found in electronic cigarette vapor, although mostly at substantially lower levels. The reduced concentrations of these chemicals in electronic cigarette vapor may imply lower health risk; however, they cannot equate to no risk. To date, the long-term health consequences of vaping are largely unknown. This “Perspective” provides a concise chronology of events leading up to an unprecedented global challenge, namely the convergence of global tobacco epidemic and youth vaping epidemic. Current state of knowledge, outstanding questions in the field, present challenges, and future directions in research are highlighted. The existing data show a continued and dynamic evolution of the converged epidemics. The goal should be to prevent youth vaping while improving smoking cessation strategies. In smokers who are unable or unwilling to quit smoking, the objective should be to provide “provably” safe or less-harmful alternatives, which should “completely” or “substantially” substitute tobacco cigarettes.

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