2010
DOI: 10.1016/j.transproceed.2010.03.132
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The Contraceptive Vaginal Ring in Women With Renal and Liver Transplantation: Analysis of Preliminary Results

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Cited by 27 publications
(9 citation statements)
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“…To avoid monthly fluctuations in drug concentrations, patients using combined methods should use them continuously, without a hormonefree interval. Although 1 study suggests that immunosuppressant concentrations remain stable with use of the contraceptive vaginal ring, 259 both the ring and the patch are sufficiently similar to COCs that, until further data are available, they should be used with the same precautions that apply to COCs. Drug interactions with progestin-only methods are uncommon; however, monitoring cyclosporine concentrations is advisable.…”
Section: Adolescent Recipients Of Solid Organ Transplantationmentioning
confidence: 99%
See 1 more Smart Citation
“…To avoid monthly fluctuations in drug concentrations, patients using combined methods should use them continuously, without a hormonefree interval. Although 1 study suggests that immunosuppressant concentrations remain stable with use of the contraceptive vaginal ring, 259 both the ring and the patch are sufficiently similar to COCs that, until further data are available, they should be used with the same precautions that apply to COCs. Drug interactions with progestin-only methods are uncommon; however, monitoring cyclosporine concentrations is advisable.…”
Section: Adolescent Recipients Of Solid Organ Transplantationmentioning
confidence: 99%
“…Patients who have established normal organ function and are stable at least 6 to 8 months after transplantation can use any of the currently available hormonal contraceptives, provided they do not have other contraindications to the estrogen component. 58,254,257,[258][259][260] Contraindications to estrogen, however, occur more commonly in transplant recipients. For example, COCs should not be prescribed to patients with active liver dysfunction or coronary artery disease.…”
Section: Adolescent Recipients Of Solid Organ Transplantationmentioning
confidence: 99%
“…Use of the contraceptive vaginal ring has been described in a prospective group of 17 renal and liver transplant patients. There were no cases of rejection, need to change immunosuppressive medication, or contraceptive failure [27]. The COCs in these studies contain both 20 and 35 mcg of estradiol and a variety of progestins.…”
Section: Combined Hormonal Contraceptionmentioning
confidence: 89%
“…41 Both the transdermal patch and vaginal ring were studied in transplant patients and had favorable results. 24,43 The combined hormonal oral contraceptive pills, patch, and ring are in category 4 (unacceptable health risk) in the US MEC in patients with complicated cases, but they are in category 2 in uncomplicated cases. 21 Combined hormonal contraceptives should not be considered first-line options by themselves for transplant patients because of their high failure rate with typical use.…”
Section: Combined Hormonal Contraceptivesmentioning
confidence: 99%