“…(iii) CR with PZQ at 40 mg/kg rose to normal when the treatment was repeated after 2 to 4 months and were also normal in children originating from the area of endemic infection but living in an urban area with no transmission (108; A. Mbaye, D. Engels, L. Tchuente, and B. Gryseels, unpublished results). (iv) The efficacy of PZQ could be related to age and pretreatment intensity but not to other host factors, including behavioral and immunological parameters (137). (v) Application of a statistical model relating egg counts more accurately to worm numbers showed that the poor CR could be explained by the initial high intensity of infection, even if over 95% of the worms were killed (S. J. de Vlas, D. Engels, A. Mbaye, and B. Gryseels, Schistosomiasis Res.…”