Preventive Conservation (PC) is the sum of the activities needed to protect cultural heritage from damage. Among PC activities, climate monitoring and control are especially necessary for anthropologic and ethnographic collections, which are highly hygroscopic. Knowledge of collection objects and their conservation needs, together with their housing characteristics, is at the base of efficient PC strategies, including the evaluation of potential changes in the environmental parameters. An approach based on international standards is required to make museum indoor climate control activities objectives needs-based, and more economically, environmentally, and energetically sustainable. This approach was implemented for the PREMUDE research project, with the collaboration of DAGRI Department of University of Florence, Sistema Museale di Ateneo (SMA) and Opificio delle Pietre Dure (OPD). In this context, national and international norms, standards and museum guidelines were examined and used to apply innovative technologies of the Internet of Things (IoT) for monitoring and climate control of case studies from the Museum of Anthropology and Ethnology of Florence.