The contribution of mobile genetic elements to the evolution and ecology of Vibrios

Hazen, Tracy H.; Li, Pan; Gu, Ji‐Dong; Sobecky, Patricia A.

doi:10.1111/j.1574-6941.2010.00937.x

Cited by 91 publications

(84 citation statements)

References 83 publications

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“…Surface association not only increases vibrio survival and fitness but also increases opportunities for vibrio intraspecies and interspecies exchanges of genes, including those for the utilization of unusual substrates and for virulence (15,(546)(547)(548)(549). Such exchanges are supported by surface-induced natural competence and likely involve plasmids, phages, transposons, integrons/gene cassettes, and perhaps other horizontal gene transfer mechanisms (550)(551)(552). QS-mediated biofilm formation can include large numbers of toxigenic V. chol-erae bacteria, usually in the viable-but-nonculturable (VBNC) state (33, 553, 554).…”

Section: An Example Of Microbial Interaction With Surfaces: Vibrio Chmentioning

confidence: 99%

Microbial Surface Colonization and Biofilm Development in Marine Environments

Dang

Lovell

2016

Microbiol Mol Biol Rev

872

636

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SUMMARYBiotic and abiotic surfaces in marine waters are rapidly colonized by microorganisms. Surface colonization and subsequent biofilm formation and development provide numerous advantages to these organisms and support critical ecological and biogeochemical functions in the changing marine environment. Microbial surface association also contributes to deleterious effects such as biofouling, biocorrosion, and the persistence and transmission of harmful or pathogenic microorganisms and their genetic determinants. The processes and mechanisms of colonization as well as key players among the surface-associated microbiota have been studied for several decades. Accumulating evidence indicates that specific cell-surface, cell-cell, and interpopulation interactions shape the composition, structure, spatiotemporal dynamics, and functions of surface-associated microbial communities. Several key microbial processes and mechanisms, including (i) surface, population, and community sensing and signaling, (ii) intraspecies and interspecies communication and interaction, and (iii) the regulatory balance between cooperation and competition, have been identified as critical for the microbial surface association lifestyle. In this review, recent progress in the study of marine microbial surface colonization and biofilm development is synthesized and discussed. Major gaps in our knowledge remain. We pose questions for targeted investigation of surface-specific community-level microbial features, answers to which would advance our understanding of surface-associated microbial community ecology and the biogeochemical functions of these communities at levels from molecular mechanistic details through systems biological integration.

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Section: An Example Of Microbial Interaction With Surfaces: Vibrio Chmentioning

confidence: 99%

Microbial Surface Colonization and Biofilm Development in Marine Environments

Dang

Lovell

2016

Microbiol Mol Biol Rev

872

636

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“…V. cholerae is known to undergo 402 HGT via transformation [49], transduction [50] and conjugation [51,52]. HGT contributes 403 substantially to drug resistance, pathogenicity and adaptation to different environments, 404 via the acquisition of genomic islands, phages, transposons, ICEs and plasmids [7,53].…”

Section: Gene Content Variation Within Patients and Its Functional Comentioning

confidence: 99%

Vibrio choleraegenomic diversity within and between patients

Levade

Terrat

Leducq

et al. 2017

Preprint

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28Cholera is a severe, waterborne diarrheal disease caused by toxin-producing 29 strains of the bacterium Vibrio cholerae. Comparative genomics has revealed "waves" of 30 cholera transmission and evolution, in which clones are successively replaced over 31 decades and centuries. However, the extent of V. cholerae genetic diversity within an 32 epidemic or even within an individual patient is poorly understood. Here, we 33 characterized V. cholerae genomic diversity at a micro-epidemiological level within and 34 between individual patients from Bangladesh and Haiti. To capture within-patient 35 diversity, we isolated multiple (8 to 20) V. cholerae colonies from each of eight patients, 36sequenced their genomes and identified point mutations and gene gain/loss events. We 37 found limited but detectable diversity at the level of point mutations within hosts (zero to 38 three single nucleotide variants within each patient), and comparatively higher gene 39 content variation within hosts (at least one gain/loss event per patient, and up to 103 40

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“…Horizontal gene transfer is thought to be extensive among the Vibrionaceae (48). The transmissibility of pPHDP70 is another example of the key role that mobile elements have had in underlying the emergence of disease-causing vibrios.…”

Section: Figmentioning

confidence: 99%

A Transmissible Plasmid-Borne Pathogenicity Island Confers Piscibactin Biosynthesis in the Fish Pathogen Photobacterium damselae subsp. piscicida

Osorio

Rivas

Balado

et al. 2015

Appl Environ Microbiol

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The fish pathogen Photobacterium damselae subsp. piscicida produces the siderophore piscibactin. A gene cluster that resembles the Yersinia high-pathogenicity island (HPI) encodes piscibactin biosynthesis. Here, we report that this HPI-like cluster is part of a hitherto-uncharacterized 68-kb plasmid dubbed pPHDP70. This plasmid lacks homologs of genes that mediate conjugation, but we found that it could be transferred at low frequencies from P. damselae subsp. piscicida to a mollusk pathogenic Vibrio alginolyticus strain and to other Gram-negative bacteria, likely dependent on the conjugative functions of the coresident plasmid pPHDP60. Following its conjugative transfer, pPHDP70 restored the capacity of a vibrioferrin mutant of V. alginolyticus to grow under low-iron conditions, and piscibactin became detectable in its supernatant. Thus, pPHDP70 appears to harbor all the genes required for piscibactin biosynthesis and transport. P. damselae subsp. piscicida strains cured of pPHDP70 no longer produced piscibactin, had impaired growth under iron-limited conditions, and exhibited markedly decreased virulence in fish. Collectively, our findings highlight the importance of pPHDP70, with its capacity for piscibactin-mediated iron acquisition, in the virulence of P. damselae subsp. piscicida. Horizontal transmission of this plasmid-borne piscibactin synthesis gene cluster in the marine environment may facilitate the emergence of new pathogens.

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The contribution of mobile genetic elements to the evolution and ecology of Vibrios

Cited by 91 publications

References 83 publications

Microbial Surface Colonization and Biofilm Development in Marine Environments

Microbial Surface Colonization and Biofilm Development in Marine Environments

Vibrio choleraegenomic diversity within and between patients

A Transmissible Plasmid-Borne Pathogenicity Island Confers Piscibactin Biosynthesis in the Fish Pathogen Photobacterium damselae subsp. piscicida

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