This article uses a modified model of the theory of planned behaviour to assess salient beliefs of household heads towards the separation of municipal solid waste at its source in the Greater Accra Region of Ghana. Structural equation modelling was used to analyse the responses of 598 household heads to a questionnaire in a cross-sectional design. Whilst the default model produced an acceptable fit to the data and explained 37% of the variance in households’ intention to separate waste at its source, the modified model with moral norms as an additional construct fitted the data excellently, explaining 52% of the variance in intention. Moral norms and perceived behavioural control were the predominant latent constructs to influence intentions. Control beliefs related to the availability of waste receptacles, provision of regular waste collection services, and access to knowledge of the separation process had the greatest tendency to facilitate households’ intentions. Pro-environmental interventions designed in a participatory manner to promote moral correctness, responsibility, respect for the environment, and positive affect may empower households to separate waste at its source. This research contributes to the development of a municipal solid waste strategy in the region, and may further support research in waste diversion and the circular economy in other jurisdictions.