The Control of Dicumarol Therapy in Myocardial Infarction by a Simple Blood Prothrombin Test

Coagulation Defects Induced by Long‐term Anticoagulant Therapy*,†

“…The Owren‐Ware‐Stragnell prothrombin time was determined as described by Ware and Stragnell (8). The Manchester prothrombin test was performed as described by Manchester and Rabkin (9). The Ware and Seegers two‐stage prothrombin determination (10) was modified by the use of bovine serum and a preparation 4 of Fraction I which had been purified by adsorption with barium sulfate and subsequent precipitation with 25 per cent ammonium sulfate.…”

Long-term Anticoagulant Treatment of Coronary Thrombosis in General Practice

“…Marked alteration in the amount of alcohol imbibed daily may cause a fluctuation in the prothrombin level (Olwin and Koppel, 1957). Any deficiency of vitamin C should be corrected and an adequate intake in the diet ensured (Wright et al, 1954;Manchester, 1957).…”