The Controversy of Conventional Psychiatric Diagnostics

Hayempour, Benjamin Jacob

doi:10.4172/2329-6895.1000122

Cited by 2 publications

(1 citation statement)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is an extremely serious condition, with ~16% of cases having a lifetime prevalence and ~60% being of clinical severity [1–3]. The characteristics of the disorder mean it can cause significant problems in regard to work performance and can also increase the economic burden of society [4,5]. Currently, diagnosis of depression relies primarily on clinicians’ rating scales and specialized questionnaires, such as the Diagnostic and Statistical Manual of Mental Disorders (DSM) [6].…”

Section: Introductionmentioning

confidence: 99%

Skin conductance responses in Major Depressive Disorder (MDD) under mental arithmetic stress

et al. 2019

View full text Add to dashboard Cite

Depressive symptoms are related to abnormalities in the autonomic nervous system (ANS), and physiological signals that can be used to measure and evaluate such abnormalities have previously been used as indicators for diagnosing mental disorder, such as major depressive disorder (MDD). In this study, we investigate the feasibility of developing an objective measure of depressive symptoms that is based on examining physiological abnormalities in individuals when they are experiencing mental stress. To perform this, we recruited 30 patients with MDD and 31 healthy controls. Then, skin conductance (SC) was measured during five 5-min experimental phases, comprising baseline, mental stress, recovery from the stress, relaxation, and recovery from the relaxation, respectively. For each phase, the mean amplitude of the skin conductance level (MSCL), standard deviations of the SCL (SDSCL), slope of the SCL (SSCL), mean amplitude of the non-specific skin conductance responses (MSCR), number of non-specific skin conductance responses (NSCR), and power spectral density (PSD) were evaluated from the SC signals, producing 30 parameters overall (six features for each phase). These features were used as input data for a support vector machine (SVM) algorithm designed to distinguish MDD patients from healthy controls based on their physiological responses. Statistical tests showed that the main effect of task was significant in all SC features, and the main effect of group was significant in MSCL, SDSCL, SSCL, and PSD. In addition, the proposed algorithm achieved 70% accuracy, 70% sensitivity, 71% specificity, 70% positive predictive value, 71% negative predictive value in classifying MDD patients and healthy controls. These results demonstrated that it is possible to extract meaningful features that reflect changes in ANS responses to various stimuli. Using these features, detection of MDD was feasible, suggesting that SC analysis has great potential for future diagnostics and prediction of depression based on objective interpretation of depressive states.

show abstract

Section: Introductionmentioning

confidence: 99%

Skin conductance responses in Major Depressive Disorder (MDD) under mental arithmetic stress

et al. 2019

View full text Add to dashboard Cite

show abstract

Challenges in Making Differential Diagnosis of Psychiatric Illness: An Occupational Therapy Perspective

Piven¹

2013

J Neurol Disord

View full text Add to dashboard Cite

This editorial has offered a commentary about the article, Limitations of Clinical Psychiatric Diagnostic Measurements by Aden Jacob, a research scientist working at the Gray Institute for Radiation Oncology and Radiobiology, Medical Physics Radiotherapy at the University of Oxford in the United Kingdom [1]. My first reaction to the article was, "Why would an oncologist write an article about the American Medical Association's limitations in classification of psychiatric diagnoses? My curiosity led me to Google to search for answers. I found the author's website. I did not seek this information to belittle or challenge the author's credentials. I thought that other readers might be curious as well.

show abstract

The Controversy of Conventional Psychiatric Diagnostics

Cited by 2 publications

References 9 publications

Skin conductance responses in Major Depressive Disorder (MDD) under mental arithmetic stress

Skin conductance responses in Major Depressive Disorder (MDD) under mental arithmetic stress

Challenges in Making Differential Diagnosis of Psychiatric Illness: An Occupational Therapy Perspective

Contact Info

Product

Resources

About