2015
DOI: 10.1016/j.surg.2015.07.018
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The conundrum of the young colon cancer patient

Abstract: Abstract:Background: Colonoscopy has had a major impact on colon cancer incidence and survival for

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Cited by 23 publications
(23 citation statements)
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“…More worryingly, its incidence in those ≤50 years of age has been increasing with the increased use of endoscopic evaluation [9][10][11]. In Singapore, the incidence of colorectal cancer was 22.5 per 100,000 per year for males between 40 and 49 years old and 20 per 100,000 per year for females of the same age group during the years 2010-2014 [8].…”
Section: Discussionmentioning
confidence: 99%
“…More worryingly, its incidence in those ≤50 years of age has been increasing with the increased use of endoscopic evaluation [9][10][11]. In Singapore, the incidence of colorectal cancer was 22.5 per 100,000 per year for males between 40 and 49 years old and 20 per 100,000 per year for females of the same age group during the years 2010-2014 [8].…”
Section: Discussionmentioning
confidence: 99%
“…Overall CRC incidence has fallen since the mid-1980s for unclear reasons initially; further decrease has been accelerated with the implementation of national screening efforts in the U.S. [8]. However, the rate is on the rise for younger Americans and more so in young Blacks [7072]. …”
Section: Introductionmentioning
confidence: 99%
“…This is consistent with our finding, that although the apparent differences in incidence are small in the young-onset group, African Americans begin to show higher increases in incidence at an earlier age. Moreover, although these incidence rates are relatively low compared to those in adults over the age of 50, this age – related disparity in the under 50 group is expected to increase further in the future with projections of newly diagnosed colon and rectal cancers expected to nearly double by 2030 [2,8]. Our investigation suggests an increased incidence of colorectal cancer in young 20-44 African Americans and lowest rates in young 20-44 APIs.…”
Section: Discussionmentioning
confidence: 75%
“…For individuals younger than the recommended screening guidelines, however, numerous studies have shown that the incidence is actually increasing [2,3,5-7]. Moreover, a study conducted by Amri et al showed that cancers diagnosed in patients younger than 50 years of age have greater rates of metastasis, positive lymph nodes and extramural vascular invasion [8]. Therefore, colorectal cancer found in young adults is more likely to be diagnosed at an advanced stage and less likely to be curable, than if diagnosed at later age [2,8,9].…”
Section: Introductionmentioning
confidence: 99%
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