The coordination chemistry of tripodal tetraamine ligands

Synthesis, Structure, and Peroxidase Activity of an Octahedral Ru(III) Complex with a Tripodal Tetraamine Ligand

“…Several metal complexes with the tpea ligand have been synthesized and they usually have formed four or five coordinated complexes. 11 However, two factors attracted us to choose the ligand as a candidate for the octahedral Ru(III) model complex: strong tendencies (i) toward the six-coordination of Ru ions and (ii) the formation of six-membered chelate rings with near perpendicular bite angles of tpea upon coordination. In this study, we have used the tpea ligand to synthesize a new model octahedral Ru(III) complex and investigated its structure and physiological reactivity.…”

Synthesis of rhodium(III) complexes with tris/tetrakis‐benzimidazoles and benzothiazoles—quick identification of cyclometallation by nuclear magnetic resonance spectroscopy

“…Other studies have illustrated how tripodal (N-heterocyclic alkyl)amine ligand design influences the geometry of the complexes and the internal exchange processes between isomers. [3,4] Gayathri et al [5,6] prepared a series of cyclometallated rhodium complexes with 1,3-bis(benzimidazolyl)benzene. The conventional 13 C NMR experiment takes longer time to detect the cyclometallated carbon because of sensitivity problem and also due to poor solubility of metal complexes in the desired solvents.…”

New Pseudopeptidic Bis(Amino Amides): Supramolecular Behaviour in the Presence of Transition Metals

“…These initial macrocyclic systems provided an important impact on supramolecular chemistry and in the understanding of naturally occurring macrocycles such as ionophores, hemes, and porphyrins. Later on, the research work pioneered by Donald Cram on macrocyclic cyclophanes, spherands, and carcerands, 10 and the great contribution from Jean-Marie…”

“…9 Then, bis(amino amides) 1 and 2 were subjected to a reductive amination process with benzaldehyde in methanol, affording the ligands 3 and 4 in good yields. 10 The selection of the central spacer containing three methylene groups was based on the results previously obtained with related ligands, showing that this spacer is very well suited to favour the formation of strong 1:1 metal complexes with the bisdeprotonated ligand.…”

“…80% overall yields) starting from commercially available N-Cbz protected amino acids through the initial formation of their activated N-hydroxysuccinimide esters, coupling with a variety of diamines, N-deprotection, and final Nsubstitution. 10 C 2 -open chain pseudopeptides I can be used as building blocks for the construction of macrocyclic structures II and III. Despite the simplicity of C 2 -pseudopeptides, changing the spacer, changing the amino acid (R), or functionalizing the amino terminal groups (X) provides a high level of molecular diversity and sites for supramolecular interactions.…”