The coronavirus disease pandemic among adult congenital heart disease patients and the lessons learnt – results of a prospective multicenter european registry

Ruperti-Repilado, Francisco Javier; Baumgartner, Helmut; Bouma, Berto J.; Bouchardy, Judith; Budts, Werner; Campens, Laurence; Chessa, Massimo; Marín, M.J. del Cerro; Gabriel, Harald; Gallego, Pastora; González, Elvira Ana; Jensen, Annette Schophuus; Ladouceur, Magalie; Lockhart, Christopher; Miranda, Berta; Morissens, Marielle; Escobar, Eduardo Moreno; Pasquet, Agnès; Soriano, Joaquín Rueda; Bosch, Annemien E. van den; Zwaan, Heleen B. van der; Tobler, Daniel; Greutmann, Matthias; Schwerzmann, Markus

doi:10.1016/j.ijcchd.2022.100428

Cited by 1 publication

(8 citation statements)

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“…Along the course of COVID-19 pandemic, the approach to the vulnerable patients given their different presentations was problematic. Professionals in charge of particularly high risk groups, such as adult patients with CHD, were forced to make difficult choices during the initial onset of the COVID-19 pandemic [ 46 ]. During the early weeks of the pandemic, pre-existing cardiovascular illnesses were discovered to be a key indicator of a poor prognosis in cases of infection with the novel SARS-CoV-2 [ 46 ].…”

Section: Discussionmentioning

confidence: 99%

“…Professionals in charge of particularly high risk groups, such as adult patients with CHD, were forced to make difficult choices during the initial onset of the COVID-19 pandemic [ 46 ]. During the early weeks of the pandemic, pre-existing cardiovascular illnesses were discovered to be a key indicator of a poor prognosis in cases of infection with the novel SARS-CoV-2 [ 46 ]. It was not known for a long time whether this link held true for the predominantly adult individuals with CHD.…”

Section: Discussionmentioning

confidence: 99%

“…It was not known for a long time whether this link held true for the predominantly adult individuals with CHD. A prospective multicenter European registry published in March 2023 attempted to assess the changes in risk stratification of adults with CHD patients [ 46 ]. By contrasting the results of two surveys given to experts in the field of adults with CHD at two different points during the pandemic, at the start and soon after the first outcome data on adults with CHD patients with COVID-19 were available, they determined changes in risk stratification of adults with CHD patients during the pandemic [ 46 ].…”

Section: Discussionmentioning

confidence: 99%

“…A prospective multicenter European registry published in March 2023 attempted to assess the changes in risk stratification of adults with CHD patients [ 46 ]. By contrasting the results of two surveys given to experts in the field of adults with CHD at two different points during the pandemic, at the start and soon after the first outcome data on adults with CHD patients with COVID-19 were available, they determined changes in risk stratification of adults with CHD patients during the pandemic [ 46 ]. The overall risk perception was lower in the second survey than it was in the first when assessing the significance of general and adults with CHD-specific risk factors for a complicated disease course in the case of COVID-19 among the patients [ 46 ].…”

Section: Discussionmentioning

confidence: 99%

“…By contrasting the results of two surveys given to experts in the field of adults with CHD at two different points during the pandemic, at the start and soon after the first outcome data on adults with CHD patients with COVID-19 were available, they determined changes in risk stratification of adults with CHD patients during the pandemic [ 46 ]. The overall risk perception was lower in the second survey than it was in the first when assessing the significance of general and adults with CHD-specific risk factors for a complicated disease course in the case of COVID-19 among the patients [ 46 ]. This was true even for risk factors related to physiological stage, which have been linked to poor prognostic outcomes in adults with CHD patients with COVID-19 [ 24 , 46 ].…”

Section: Discussionmentioning

confidence: 99%

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COVID-19 in Cyanotic Congenital Heart Disease

Ammar

Nassar

Bitar

et al. 2023

Canadian Journal of Infectious Diseases and Medical Microbiolog

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Congenital heart disease (CHD) is the most prevalent congenital defect in newborn infants. Due to the various types of heart abnormalities, CHD can have a wide range of symptoms. Cardiac lesions comprise a range of different types and accordingly varying severities. It is highly helpful to classify CHD into cyanotic and acyanotic heart diseases. In this review, we are investigating the course of Coronavirus disease 2019 (COVID-19) in cyanotic CHD patients. The infection may directly or indirectly affect the heart by affecting the respiratory system and other organs. The effect on the heart that is pressure- or volume-overloaded in the context of CHD is theoretically more severe. Patients with CHD are at a higher risk of mortality from COVID-19 infection or suffering worse complications. While the anatomic complexity of CHD does not seem to predict the severity of infection, patients with worse physiological stages are more susceptible such as cyanosis and pulmonary hypertension. Patients with CHD exhibit continuous hypoxemia and have lower oxygen saturations because of a right-to-left shunt. Such individuals run the danger of rapidly deteriorating in the event of respiratory tract infections with inadequate oxygenation. Additionally, these patients have a higher risk of paradoxical embolism. Hence, critical care should be given to cyanotic heart disease patients with COVID-19 in comparison to acyanotic patients and this is through proper management, close observation, and adequate medical therapy.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%