The corpus callosum: Some anatomical and functional considerations with special reference to language

Impact of HIV infection and alcohol on cognition: a review

“…The effects were most pronounced in individuals with advanced HIV infection or acquired immunodeficiency syndrome (AIDS). 19 Although the role of the corpus callosum in higher cognitive functions still remains poorly defined, 20 the authors reported an association between degradation of corpus callosum microstructure and performance on measures of motor speed. These findings of early structural alterations in the corpus callosum are particularly interesting because very heavy alcohol use by non-HIV-infected individuals can be associated with global demyelination of the fibers of the corpus callosum.…”

The Ontogeny of Cerebral Language Dominance

“…The idea that the corpus callosum may be ideally suited for this task has been around for some time (Selnes, 1974). It may also have been prematurely dismissed (Cook, 1984).…”

Review of Geschwind, Cohen & Wartofsky (1974): Selected Papers on Language and the Brain

“…A damaged left side will still emit inhibitory discharges to the non-dominant hemisphere and thus prevent it from functioning at its full capacity. Seines (1974) on the other hand feels that perhaps there is initial inhibition by the callosal structures during early neurophysiological development to aid the lateralization process. However, these inhibitory mechanisms soon subside, and the right hemisphere remains deficient for language --as does the the left for non-verbal functions.…”

“…However, these inhibitory mechanisms soon subside, and the right hemisphere remains deficient for language --as does the the left for non-verbal functions. An interesting argument against the callosum as inhibitor of the right in aphasics is advanced by Seines (1974). He reasons that if the callosum, as part of its normal function, is inhibiting the right then why doesn't the aphasie speech actually improve upon Amytal injections into the left carotid?…”