The correlation between ECochG parameters and early auditory behavior after cochlear implantation in children

Abstract

All children with AS/AN and SNHL benefit to a similar extent from CI. The preoperatively assessed CAP/SP ratio has a prognostic value for the development of auditory behavior following CI.

Clinical role of electrocochleography in children with auditory neuropathy spectrum disorder

“…Patients with ANSD are often treated with cochlear implants (CI), however, their outcomes are highly variable; some subjects perform as well as the best CI users with hearing loss due to non-ANSD etiologies, while others never achieve open-set speech perception [8, 10–12, 15, 16]. When comorbidities are absent or controlled for, the outcomes in ANSD and non-ANSD CI recipients are not significantly different [17–19].…”

“…When comorbidities are absent or controlled for, the outcomes in ANSD and non-ANSD CI recipients are not significantly different [17–19]. Still, no specific factors highly predictive of speech perception outcomes in ANSD patients have been identified [12, 16, 20]. The site-of-lesion appears to have prognostic significance: abnormalities restricted to the inner hair cells, the synapse, and the terminal dendrites of the auditory nerve allow for better CI outcomes than pathologies of spiral ganglion cells, myelination, or the central nervous system (CNS) [2, 7, 11, 19, 21–24].…”

“…Electrocochleography (ECochG) provides a possible objective measure to evaluate the peripheral auditory system of CI candidates including those diagnosed with ANSD [1, 16, 22, 25, 26]. By examining the origins and magnitude of the potentials recorded with ECochG we may improve our understanding of the variation in speech perception outcomes.…”

“…By examining the origins and magnitude of the potentials recorded with ECochG we may improve our understanding of the variation in speech perception outcomes. The stimuli previously used for evaluation have typically been clicks or high frequency tone pips; the ECochG components produced by these are the CM, summating potential (SP) and compound action potential (CAP) [16, 27–30]. Our approach is to utilize a wide range of tone frequencies, because most responses in CI subjects are to low frequencies [25, 26, 31, 32].…”

Task force Guideline of Brazilian Society of Otology – hearing loss in children – Part II — Treatment

“…Precisely determining the site of the lesion causing neuropathy, by using molecular diagnosis combined with electrophysiologic data from electrocochleography as well as intraoperative Electrical ABR (EABR), may help predict postoperative CI outcomes and may assist in the final treatment decision. 82 , 83 Due to the extreme genetic heterogeneity of deafness, adequate studies require a large number of patients. Thus, any study intended to report results for patients with ANSD and CI must include: (1) a detailed clinical history of the patient, with family history of neuropathy, vision loss, or vestibular disorders.…”