The Correlation between Feed-Intake Cycle and Nutritional Zinc-Deficient Status in Rats.

Yamasaki, Kazuhiro; Kaneko, Masae; Matsuda, Koichi; Sakata, Shigeko Fujimoto; Tamaki, Nanaya

doi:10.3177/jnsv.45.621

Cited by 9 publications

(24 citation statements)

References 18 publications

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“…The amplitude of the food intake cycle is correlated and inversely correlated to the addition of Zn to a Zn-deficient diet (1, 13) and a subcutaneous injection (14), respectively. The level of values (MϪA) on the bottom of the feed intake cycles is decreased but the values of the average food intake (M) are increased by addition of various concentrations of Zn (13,14). These results suggest that the ability to perceive a negative energy balance following action for food intake may depend on the level of Zn in rats and may relate to a retardation of growth in the Zn-deficient rats.…”

Section: Discussionmentioning

confidence: 72%

“…After changing their preference from sucrose to maltose, the food intake cycle was maintained with a fixed period of 3.6-d. The periods of food intake cycles changed within a narrow range of 3.5-4.0 d following the addition of Zn in the Zn-deficient rats (13,14). The Zn-adequate control rats also may have a 3.5-4.0 d food intake cycle, but the difference between the top and the bottom of the food intake cycle is very small, and so may not be noticeable.…”

Section: Discussionmentioning

confidence: 99%

“…The daily food intake of rats fed a Zn-deficient diet shows a characteristic variation and fits well to a cosine curve (12)(13)(14). But force-feeding Zn-deficient rats with 140% of their voluntary intake rapidly induces severe signs of illness ( 5 ).…”

mentioning

confidence: 93%

“…Daily food intake and body weight change data from Zn-deficient rats were analyzed by the Cosinor method (12)(13)(14). Food intake ( F ) and body weight change ( ⌬ B ) on day t were determined using the following equation:…”

Section: Methodsmentioning

confidence: 99%

“…A reduction of the protein content of the Zn-deficient diet from 20 to 5% results in no effect on food intake and disappearance of the cyclical pattern of intake ( 5 , 7 , 21 ). The value of the amplitude is decreased and the mesor is increased with increasing Zn supplementation by oral feeding ( 13 ) and subcutaneous injection ( 14 ) in the food intake cycle of Zn-deficient rats. When Zn deficient rats selected a diet from glucose and fructose diets with a two-choice method ( 22 ) and from dextrin, maltose and glucose diets with a three choice method ( 23 ), some rats changed their preference in the course of the experimental periods but the total daily food intake of the rats continued to show a 3.5-4.0 d-cycle ( 22 , 23 ).…”

mentioning

confidence: 99%

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Change to a Preference for Maltose from Sucrose over Days in Zn-Deficient Rats Selecting from Maltose and Sucrose Diets

Horikawa

Yamamoto

Matsuda

et al. 2009

J Nutr Sci Vitaminol

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Summary This paper describes a preference for two disaccharides in the diets of Zn-adequate and Zn-deficient rats. Maltose and sucrose were used as a source of carbohydrate in the diet and the selection patterns of rats were analyzed for 28 d by a two-choice selection method. Diets provided as a set of two either Zn-adequate or Zn-deficient diets were changed in position daily. Control Zn-adequate and Zn-deficient rats both exclusively selected the sucrose diet at days 1 and 2, after onset of the feeding experiment, and then gradually selected the maltose-diet. After changing their preference from sucrose to maltose, the Znadequate control rats selected widely from both the maltose and sucrose diets, while the Zndeficient rats exclusively and continuously selected the maltose diet from the two diets over the experimental period. The level of selection of sucrose-diet on day 28 had a correlation with the intestinal sucrase activity in the control rats. The sum of daily maltose and sucrose diet intake in rats fed a Zn-deficient diet showed a characteristic variation with the cyclic period of 3.6 Ϯ 0.2 d. The daily body-weight change of rats fed a Zn-deficient diet was well synchronized with their own food intake cycle. The day before changing preference from sucrose to maltose in rats fed a Zn-deficient diet represented a trough in their own food intake and body-weight cycles. These results suggest that one sign of a change in preference from sucrose to maltose in Zn-deficient rats is caused by a stage of negative energy balance.

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Section: Discussionmentioning

confidence: 72%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 93%

Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 99%

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Change to a Preference for Maltose from Sucrose over Days in Zn-Deficient Rats Selecting from Maltose and Sucrose Diets

Horikawa

Yamamoto

Matsuda

et al. 2009

J Nutr Sci Vitaminol

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Tracing of Zinc Nanocrystals in the Anterior Pituitary of Zinc-Deficient Wistar Rats

Kuldeep

Nair

Bedwal

2016

Biol Trace Elem Res

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The aim of this study was to trace zinc nanocrystals in the anterior pituitary of zinc-deficient Wistar rats by using autometallographic technique. Male Wistar rats (30-40 days of age, pre-pubertal period) of 40-50 g body weight were divided into the following: the ZC (zinc control) group-fed with 100 ppm zinc in diet, the ZD (zinc-deficient) group-fed with zinc-deficient (1.00 ppm) diet and the PF (pair-fed) group-received 100 ppm zinc in diet. The experiments were set for 2 and 4 weeks. Pituitary was removed and processed for the autometallographic technique. The control and pair-fed groups retained their normal morphological features. However, male Wistar rats fed on zinc-deficient diet for 2 and 4 weeks displayed a wide range of symptoms such as significant (P < 0.05) decrease in diet consumption, body weight and pituitary weight and decrease in gradation of intensity of zinc nanocrystals in the nuclei. The present findings suggest that the dietary zinc deficiency causes decreased intensity of zinc nanocrystals localization and their distribution in the pituitary thereby contributing to the dysfunction of the pituitary of the male Wistar rats. The severity of zinc deficiency symptoms progressed after the second week of the experiment. Decreased intensity of zinc nanocrystals attenuates the pituitary function which would exert its affect on other endocrine organs impairing their functions indicating that the metabolic regulation of pituitary is mediated to a certain extent by zinc and/or hypothalamus-hypophysial system which also reflects its essentiality during the period of growth.

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Effect of dietary zinc deficiency on testes of Wistar rats: Morphometric and cell quantification studies

Kumari

Nair

Bedwal

2011

Journal of Trace Elements in Medicine and Biology

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The Correlation between Feed-Intake Cycle and Nutritional Zinc-Deficient Status in Rats.

Cited by 9 publications

References 18 publications

Change to a Preference for Maltose from Sucrose over Days in Zn-Deficient Rats Selecting from Maltose and Sucrose Diets

Change to a Preference for Maltose from Sucrose over Days in Zn-Deficient Rats Selecting from Maltose and Sucrose Diets

Tracing of Zinc Nanocrystals in the Anterior Pituitary of Zinc-Deficient Wistar Rats

Effect of dietary zinc deficiency on testes of Wistar rats: Morphometric and cell quantification studies

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