The correlation between osseointegration and bonding strength at the bone-implant interface: In-vivo &amp; ex-vivo investigations on hydroxyapatite and hydroxyapatite/titanium coatings

Ghadami, Farhad; Hamedani, Mohsen; Rouhi, Gholamreza; Saber-Samandari, Saeed; Farzad‐Mohajeri, Saeed; Mashhadiabbas, Fatemeh

doi:10.1016/j.jbiomech.2022.111310

Cited by 9 publications

(2 citation statements)

References 34 publications

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“…In-vivo & ex-vivo investigations on HA and HA/Ti coatings (2022). PMID: 36162145 [94] Ghadami F, Amani Hamedani M, Rouhi G, Saber-Samandari S, Mehdi Dehghan M, Mashhadi-Abbas F Farzad-Mohajeri S,…”

Section: Study/year Author Study Description Study Arms Resultsmentioning

confidence: 99%

Application of Hydroxyapatite in Regenerative Dentistry

George Ittycheria,

George,

John

et al. 2024

Biomedical Engineering

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In clinical practice, dentists face alveolar bone loss that needs to be managed by bone grafts. The basic bone grafting materials are autograft, allograft, xenograft, and alloplasts. Autografts are gold standard because it has osteoconduction osteoinduction osteogenic. However, they possess risk for the morbidity of the donor site and limited availability. Allograft have possibility of disease transmission and immunologic reactions. These problems potentiated the use of alloplasts. For bone regeneration, hydroxyapatite is the reference material because of its biocompatibility, bioactivity, osteoconductivity, and osteoinductive property. Natural hydroxyapatite can be synthesized from fishbone, coral, bovine bone, eggshell, and seashells. Hydroxyapatite bone substitute has ideal properties for socket preservation, sinus augmentation, periodontal regeneration and in restorative and preventive dentistry. When used as implant coatings, they support osseointegration and osteogenesis. Hydroxyapatite known for its bone regenerative capacity. Nano-hydroxyapatite, with smaller size and wider surface area, permits more proteins and cells to attach to the surface speed up regeneration. Hydroxyapatite are used as inorganic building blocks for tissue engineering or as nano-fillers with polymers. Furthermore, ion doping and surface modifications have been reported to prepare functionalized hydroxyapatite. This chapter illustrates the role of hydroxyapatite in regenerative dentistry, and advances and advantages of using it as a component of other dental materials, whether experimental or commercially available.

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Section: Study/year Author Study Description Study Arms Resultsmentioning

confidence: 99%

Application of Hydroxyapatite in Regenerative Dentistry

George Ittycheria,

George,

John

et al. 2024

Biomedical Engineering

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“…Studies employing tiny diameter Ti-Zr implants in humans in vivo [5,163,164] shown that these materials display osseointegration similar to that of cpTi. This study found that both the success rates and implant life were satisfactory.…”

Section: Osseointegrationmentioning

confidence: 99%

A review—metastable β titanium alloy for biomedical applications

Pesode

2023

J. Eng. Appl. Sci.

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Titanium and its alloys have already been widely used as implant materials due to their outstanding mechanical characteristics and biocompatibility. Notwithstanding this, researchers and businesses alike have continued to actively pursue superior alloys since there are still problems which need urgent consideration. One of these is a noteworthy difference in the implant material’s elastics modulus and that of natural bone, which result into an issue of stress shielding. With prolonged use Ti alloys releases dangerous ions. The Ti alloy surface has a low bioactivity, which prolongs the healing process. β-Ti alloys could be used as viable alternatives when creating dental implants. Additionally, β-Ti alloys characteristics, such as low Young modulus, increased strength, appropriate biocompatibility, and strong abrasion and corrosion resistance, serve as the necessary evidence. Ti alloys when altered structurally, chemically, and by thermomechanical treatment thereby enabling the creation of material which can match the requirements of a various clinical practise scenarios. Additional research is needed which can focused on identifying next century Ti alloys consisting of some more compatible phase and transforming the Ti alloys surface from intrinsically bioinert to bioactive to prevent different issues. In order to give scientific support for adopting β-Ti-based alloys as an alternative to cpTi, this paper evaluates the information currently available on the chemical, mechanical, biological, and electrochemical properties of key β-titanium alloys designed from the past few years. This article is also focusing on β-titanium alloy, its properties and performance over other type of titanium alloy such as α titanium alloys. However, in-vivo research is needed to evaluate novel β titanium alloys to support their use as cpTi alternatives.

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Enhancing Titanium-Osteointegration: Antimicrobial, anti-inflammatory and osteogenic properties of multifunctional coatings through Layer-by-Layer Self-Assembly

Xu,

Wang,

et al. 2025

Applied Surface Science

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The correlation between osseointegration and bonding strength at the bone-implant interface: In-vivo & ex-vivo investigations on hydroxyapatite and hydroxyapatite/titanium coatings

Cited by 9 publications

References 34 publications

Application of Hydroxyapatite in Regenerative Dentistry

Application of Hydroxyapatite in Regenerative Dentistry

A review—metastable β titanium alloy for biomedical applications

Enhancing Titanium-Osteointegration: Antimicrobial, anti-inflammatory and osteogenic properties of multifunctional coatings through Layer-by-Layer Self-Assembly

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