The Correlation between the Ratio of Visceral Fat Area to Subcutaneous Fat Area on Computed Tomography and Lipid Accumulation Product as Indexes of Cardiovascular Risk

Kwon, Sohee; Han, A Lum

doi:10.7570/jomes.2019.28.3.186

Cited by 18 publications

(24 citation statements)

References 31 publications

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“…In the present study, we found that the AFI significantly correlated with BMI, presence of comorbidities, and lipid profile parameters, confirming its role as a surrogate for obesity and excessive fat accumulation. In agreement with our findings, Kwon et al, demonstrated that higher AFI was independent predictor of higher BMI [23] . Another report showed similar findings [24] .…”

Section: Discussionsupporting

confidence: 94%

Association between Abdominal Wall Fat Index (AFI) on Ultrasonography with Carotid Intima Media Thickness (CIMT) and Lipid Profile

Monib¹,

Abdelrahman

2021

The Medical Journal of Cairo University

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Background: Many international organizations have recognized obesity as a chronic disease, with significant contribution to the global mortality and morbidity. Besides, obese patients are at higher risk of death than non-obese individuals. Obesity is a major driver for disability, early retirement, and psychological disorders as well.Abdominal wall fat index (AFI) is a widely utilized sonographic measure for regional fat accumulation; it is calculated as a ratio of the highest to lowest preperitoneal and subcutaneous fat thicknesses, respectively. Carotid Intima Media Thickness (CIMT) is a well-established marker for early atherosclerosis.In this study we investigated the relationship between abdominal wall fat index (AFI) and Carotid Intima Thickness (CIMT) with lipid profile among overweight and obese patients. Aim of Study:Investigating the relationship between abdominal wall fat index (AFI) and Carotid Intima Media Thickness (CIMT) as measured by ultrasonography with lipid profile among overweight and obese patients.Patients and Methods: We conducted a cross-sectional study on 60 adult participants ranging from 22 to 66 years old of both genders. The patients were divided into three groups according to the AFI value into: Group I (AFI <0.7), group II (AFI <1.4), and group III (AFI ≥ 1.4). AFI and CIMT measured using ultrasonography and lipid profile was obtained.Results: Participants in group III (mean=53.7 ± 11.0 years old) were significantly older than other studied groups; and were more likely to be hypertensive and diabetic. There was a statistically significant difference between studied groups regarding body mass index (BMI; p=0.001), the highest level was among group III (mean BMI=34.1 ±5.8Kg/m 2 ). There were positive correlations between lipid profile parameters and the AFI. Furthermore, there was a statistically significant difference between groups regarding CIMT (p=0.001). CIMT was the highest among group III (mean of 1.4 ±0.3mm), followed by group II (mean of 1.2 ±0.3mm), and group I

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Section: Discussionsupporting

confidence: 94%

Association between Abdominal Wall Fat Index (AFI) on Ultrasonography with Carotid Intima Media Thickness (CIMT) and Lipid Profile

Monib¹,

Abdelrahman

2021

The Medical Journal of Cairo University

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“…First, LAP has been considered as an index for visceral fat and study has demonstrated that LAP is effective to predict visceral fat. 16 However, we did not assess visceral fat by computed tomography or magnetic resonance imaging, which are more accurate. Second, the influence of lifestyle factors on UA levels was not taken into consideration in the current study, which should be considered in the future researches.…”

Section: Discussionmentioning

confidence: 99%

“…Studies have demonstrated that LAP is effective to predict visceral fat. [16][17][18] To date, a number of studies have been designed to focus on the association of LAP with hypertension, diabetes, non-alcoholic fatty liver disease, and cardiovascular disease. [19][20][21][22] But there is less evidence about the association between LAP and hyperuricemia.…”

Section: Introductionmentioning

confidence: 99%

<p>Urine Glucose Excretion Attenuates the Association Between Lipid Accumulation Product and Serum Uric Acid in Subjects with Prediabetes</p>

Chen

Liu

Guo

et al. 2020

DMSO

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Purpose: Obesity is known to be strongly associated with hyperuricemia. Moreover, the impact of urine glucose excretion (UGE) on serum uric acid (UA) levels has gained much more attention in recent years. Yet concern is raised about whether UGE influences the relationship between obesity and hyperuricemia. The aim of this study was to assess the effect of UGE on the association between lipid accumulation product (LAP), a novel marker of visceral adipose accumulation, and UA in subjects with prediabetes. Materials and Methods: Data were obtained from a cross-sectional study. A total of 3645 subjects with prediabetes were included in the present study. The separate and joint associations of LAP and UGE with hyperuricemia were examined using logistic regression analyses. Results: LAP was positively associated with UA in both genders. Subgroup analysis based on UGE revealed that the association was strongest in subjects with low UGE (r = 0.328, p < 0.001), whereas the positive association was weakened, but still remained significant in subjects with moderate and high UGE. High LAP was significantly associated with an increased odds ratio for hyperuricemia after adjustment for potential confounders in the overall population (OR = 2.07, 95% CI: 1.66-2.58, p < 0.001). However, a downward trend in odds ratios for hyperuricemia was observed across UGE categories. In addition, the joint association analysis confirmed that the relationship between LAP and hyperuricemia was attenuated by UGE. Conclusion: The positive association between LAP and UA appears to be attenuated by UGE, indicating that promoting UGE may be an effective strategy for controlling UA levels, especially for people with obesity who are at increased risk for hyperuricemia.

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“…The TG/HDL-C ratio is an unsophisticated tool to ascertain patients at increased risk for insulin resistance and CVD. It is used to determine subjects at risk and vary across ethnicity and race [7]. Ioachimescu [30] and Bruna [1] also detected correlations with LAP Index and fasting glucose, HDL-C and SBP in both general population and in patients at higher cardiovascular risk.…”

Section: Discussionmentioning

confidence: 99%

“…Its superiority is the simultaneous reflection of the anatomical and physiological changes of fat over accumulation in adults. According to international studies, LAP can demonstrate risk factors associated with CVD fairly well [7].…”

Section: Introductionmentioning

confidence: 99%

Lipid Accumulation Product as an Index for Visceral Obesity and Cardiovascular Risk among a Sample of Obese Egyptian Women

Hassan

El-Masry

El-Saeed

et al. 2021

Open Access Maced J Med Sci

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Background:Lipid accumulation product (LAP) is one of the indices that can demonstrate cardiovascularrisk factors according to international studies. Aim: To evaluate relationship between LAP, visceral obesity and different cardio vascular risk factors among sample of obese Egyptian Women. Methods: A retrospective cross-sectional observational study included 350 obese Egyptian women; aged 25- 55 years. They were subjected to blood pressure and anthropometric assessment (weight, height and waist circumference), abdominal ultrasound (visceral fat) and laboratory tests (fasting blood sugar and lipid profile).Results: The majority of the participated women had wide WC (88.9%) and increased visceral fat (80.6%). Hyperglycemia was present among (47.4%), hypertension among 42.6%, high triglycerides among 26.6% and low HDL among 44.3%. The odds of obtaining LAP >80.74 cm.mmol/L (4th quartile) is 2.7 times higher in individuals with hypertension(BP > 130/85),and 6.79 times higher in individuals with visceral fat ≥ 5 cm. Depending on the visceral fat as a standard for classification of visceral obesity (>5 cm for women), revealed that the AUCs of LAP was 0.752 (95% CI 0.697–0.806) in women. The cutoff point of LAP;for prediction of visceral obesity among Egyptian women, was 61.69; using ROC analysis; with sensitivity 68% and specificity 75% and PPV/NPV 1.05 and accuracy 71.5% .Conclusion: LAP index had significant correlations with visceral obesity and hypertension. The cutoff point of LAP 61.69 can be used to predict visceral obesity among Egyptian women.

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The Correlation between the Ratio of Visceral Fat Area to Subcutaneous Fat Area on Computed Tomography and Lipid Accumulation Product as Indexes of Cardiovascular Risk

Cited by 18 publications

References 31 publications

Association between Abdominal Wall Fat Index (AFI) on Ultrasonography with Carotid Intima Media Thickness (CIMT) and Lipid Profile

Association between Abdominal Wall Fat Index (AFI) on Ultrasonography with Carotid Intima Media Thickness (CIMT) and Lipid Profile

<p>Urine Glucose Excretion Attenuates the Association Between Lipid Accumulation Product and Serum Uric Acid in Subjects with Prediabetes</p>

Lipid Accumulation Product as an Index for Visceral Obesity and Cardiovascular Risk among a Sample of Obese Egyptian Women

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