The correlation of irregularities in carotid arterial intima-media thickness with coronary artery disease

Abstract

Noninvasive ultrasonographic assessment of carotid artery intima-media thickness (IMT) can improve risk stratification for coronary artery disease (CAD) in certain patients. Several measurements have been used to evaluate carotid atherosclerosis by ultrasonography. Although it has been reported that angiographic arterial irregularities correlate with pathologic changes of atherosclerosis and the occurrence of cardiovascular events, only a few studies have assessed carotid arterial wall irregularity by ultrasonography. The purpose of this study was to evaluate the irregularity of IMT quantitatively, and its association with the presence or absence of CAD. The correlation of maximum and mean IMT values, and IMT irregularity with the presence or absence of CAD, was investigated in 90 patients who had undergone coronary angiography. IMT was measured by manual tracking of the far wall of the common carotid arteries, carotid bulbs, and internal carotid arteries. The IMT irregularity was defined as the root mean square (RMS) difference between each IMT and averaged IMT. Multiple logistic regression analysis, after adjustment for coronary risk factors, indicated that the RMS difference was a more accurate predictor of CAD than were the mean or maximum IMT values. These results indicate that the evaluation of IMT irregularity by ultrasonography is a useful predictor for the presence of coronary atherosclerosis.

Noninvasive Assessment of Atherosclerosis in Patients with Isolated Hypertension

“…In the study of Gunes et al 9 AVP was 28.3 ± 10.4 cm/sec in patients with CAD and 57.3 ± 9.1 cm/sec in patients having normal coronary arteries. In the study of Ishizu et al, 30 CIMT was 1.14 ± 0.39 mm in patients with CAD and 0.82 ± 0.24 mm in patients having normal coronary arteries. Compared to the values in CAD patients in these studies, in our study mean AVP was relatively higher and mean CIMT was relatively lower.…”

Neutrophil–Lymphocyte Ratio and Carotid–Intima Media Thickness in Patients With Behçet Disease Without Cardiovascular Involvement

“…9 The carotid intima-media thickness (cIMT) is a marker of cardiovascular risk. 10 To the best of our knowledge, there is no study regarding the assessment of N/L ratio in patients with BD in the literature. Therefore, we evaluated the N/L ratio in patients with BD and compared it with control participants.…”

Carotid Intima-Media Thickness in Patients With Slow Coronary Flow and Its Association With Neutrophil-to-Lymphocyte Ratio

“…2 Carotid intima-media thickness (CIMT) is a marker of systemic inflammation, and it is widely used as a prominent marker for cardiovascular diseases. 3 Among several atherosclerotic surrogates, increased CIMT was positively related to coronary artery severity and cardiovascular event; therefore, it was regarded as an early indicator of overall atherosclerosis. On the other hand, CIMT was significantly increased in patients with SCF than in controls.…”