The correlation of SYNTAX score by coronary angiography with breast arterial calcification by digital mammography

Ružičić, Dušan; Dobrić, Milan; Vukovic, Mira; Dragan, Hrncic; Đorđević, Slavica; Ruzicic, M Milijana; Aleksandrić, Srđan; Đorđević-Dikić, Ana; Beleslin, Branko

doi:10.1016/j.crad.2017.12.002

Cited by 17 publications

(13 citation statements)

References 29 publications

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“…We estimated that the -cut point‖ for the SYNTAX score in the one-year MACE is 22 (18.8 to 24.5). In the reports of other authors, the values for the SYNTAX score defined by the mentioned interval are similar, both in the prediction of MACE [17,29], and in the assessment of associated risk factors in severe CAD forms [30,31].…”

Section: Discussionsupporting

confidence: 52%

Development of one-year major adverse cardiac events risk index in patients with acute coronary syndrome and diabetes mellitus who underwent percutaneous coronary intervention

et al. 2020

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Background/Aim. Patients with acute coronary syndrome (ACS) and diabetes mellitus (DM) have an increased risk of major adverse cardiovascular events (MACE) after percutaneous coronary intervention (PCI), which is not estimated sufficiently-multidimensionally in terms of type and severity of the ACS and/or DM and angiographic findings. The study was intended to validate and develop an index of metabolic, angiographic, anatomic and clinical risk factors for one-year MACE after conducted PCI in patients with ACS and DM. Methods. A prospective cross-section study was performed in patients with DM and ACS. In the PCI period the following risk factors where were recorded: 1) age and metabolic variablesglycosylated hemoglobin (HbA1c), total cholesterol, triglyceridemia; 2) endocrinological variables-DM therapy, tip of DM; 3) ACS modality; 4) radiological / anatomical variable-SYNTAX score and 5) clinical variables in modified ACEF score. One-year MACE were recorded. Results. From a total of 136 consecutive patients, 55 of them developed at least one MACE in one-year followup. A high predictive risk index was evaluated that assessed particularly or associated risks for one-year MACE (c statistic = 0.879) in the study population, defined by: SYNTAX score > 21, modified ACEF score > 1.38, HbA1c ≥ 8 (%), triglyceridemia ≥ 2.3 (mmol/L) in patients with insulin therapy, and ACS modalityunstable angina pectoris. The constructed Risk Index for one-year MACE (MACERI) has better predictive characteristics than SYNTAX score (c statistic = 0.798), as well as ACF score (c statistic = 0.744). Conclusions. MACERI can potentially have great application in future risk factors studies for one-year MACE in patients with DM and ACS who underwent PCI, because with it the effects of these factors measure multidimensionally at valid and accurate manner.

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Section: Discussionsupporting

confidence: 52%

Development of one-year major adverse cardiac events risk index in patients with acute coronary syndrome and diabetes mellitus who underwent percutaneous coronary intervention

et al. 2020

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“…Table 2 summarizes current evidence of the association between BAC and coronary atherosclerosis. 3) 8) 9) 10) 11) 12) 13) 14) 15) 16) 17) 18) 19) 20) 21) 22) 23) 24) 25) Initially, several studies examined the relationship of BAC with coronary atherosclerosis based on a coronary angiography diagnosis. The results were inconsistent across the studies and a 5-study meta-analysis by Abi Rafeh et al 26) , including nearly 1000 women, demonstrated that patients with BAC had a 1.59-fold increased risk of CAD by angiography.…”

Section: Association Of Bac and Coronary Atherosclerosismentioning

confidence: 99%

Breast Arterial Calcification: A Potential Surrogate Marker for Cardiovascular Disease

Suh

Yun

2018

J Cardiovasc Imaging

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Breast arterial calcifications (BAC), frequently observed on screening mammography, have been considered as an incidental finding without increased risk for breast cancer. They are medial calcifications and therefore, are indicative of arteriosclerosis. Previous studies indicated that the risk factors of BAC partly overlap with those of cardiovascular disease (CVD), and the presence of BAC is associated with prevalent and incident CVD. This suggests that medial arterial calcification might contribute to CVD through a pathway distinct from the intimal atherosclerotic process. A recent study showed that the presence and severity of BAC are associated with the presence of coronary artery calcification or plaques on coronary computed tomography angiography in asymptomatic women aged more than 40 years. In addition, BAC provided an independent and incremental predictive value over conventional risk factors. Given that population-based mammography screening is currently recommended in asymptomatic women, the evaluation of BAC may be helpful in identifying high-risk women without additional cost or radiation exposure.

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“…В крупном когортном исследовании 12084 женщин, принимавших участие в программе популяционного скрининга рака молочной железы (DOM Project) с длительностью наблюдения [16][17][18][19]…”

Section: связь кма с распространенностью и смертностью от ссзunclassified

“…В группе из 102 женщин в возрасте >45 лет проведено сопоставление степени поражения коронарного русла, оцениваемой по SYNTAX score, и тяжести КМА по 4-х балльной шкале [16]. Отмечено, что высокие значения показателя SYNTAX score >22 ассоциировались с большей степенью тяжести КМА (p<0,001).…”

Section: кма и ангиографически доказанная ибсunclassified

Mammographic Screening as a Tool for Cardiovascular Risk Assessing. Part 2. Association of Breast Arterial Calcification and Cardiovascular Diseases

Bochkareva

Kim

Butina

et al. 2019

Racionalʹnaâ farmakoterapiâ v kardiologii

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Prospects for the use of mammographic detection of breast arterial calcification (BAC) to improve the stratification of cardiovascular risk in the female population are of increasing interest. The purpose of the 2 part of the review is the analysis of modern literature on the relationship of the BAC with the prevalence and mortality from cardiovascular diseases (CVD). The presence of BAC on mammograms is associated with a higher likelihood of myocardial infarction, death from coronary heart disease (CHD) and CVD, as well as a 3.5-fold increase in the risk of CHD and a 5-year coronary incident (p=0.003). Women with BAC have a higher likelihood of coronary artery disease detected during angiography than women without BAC (p<0.001). Severe BAC has a stronger association with CVD than mild calcification. The association of BAC with cerebrovascular diseases and a 1.4-fold increase in the risk of ischemic stroke (p=0.004), atheromatosis of the carotid arteries and an increase in the thickness of the intima-media complex is shown. BAC is associated with atherosclerotic lesions of peripheral arteries and a decrease in the ankle-brachial index <0.9 (p=0.048). In women with chronic kidney disease, the presence of BAC indicates a 4.5-fold increase in the risk of complications associated with impaired blood flow in peripheral arteries. It is shown that the addition of BAC to the generally accepted (standard) vascular risk assessment algorithms Framingham Risk Score and Pooled Cohort Equation significantly increases the accuracy of prediction of CHD (p=0.02 and p=0.010, respectively). The detection of BAC on mammographic screening is a new promising direction for cardiovascular prophylaxis in women and opens up new opportunities for identifying groups of people with subclinical forms of CVD and high cardiovascular risk.

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The correlation of SYNTAX score by coronary angiography with breast arterial calcification by digital mammography

Cited by 17 publications

References 29 publications

Development of one-year major adverse cardiac events risk index in patients with acute coronary syndrome and diabetes mellitus who underwent percutaneous coronary intervention

Development of one-year major adverse cardiac events risk index in patients with acute coronary syndrome and diabetes mellitus who underwent percutaneous coronary intervention

Breast Arterial Calcification: A Potential Surrogate Marker for Cardiovascular Disease

Mammographic Screening as a Tool for Cardiovascular Risk Assessing. Part 2. Association of Breast Arterial Calcification and Cardiovascular Diseases

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