The correlation of the defibrillation threshhold and the upper limit of vulnerability using catheter-patch defibrillating electrodes

Kavanagh, Katherine M.; Harrison, Jenny; Dixon, E. G.; Smith, William M.; Wharton, J. Marcus; Ideker, Raymond E.

doi:10.1016/0735-1097(90)92007-o

Journal of the American College of Cardiology

1990

DOI: 10.1016/0735-1097(90)92007-o

|View full text |Cite

The correlation of the defibrillation threshhold and the upper limit of vulnerability using catheter-patch defibrillating electrodes

Katherine M. Kavanagh¹,

Jenny Harrison²,

E. G. Dixon³

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1992

1996

Publication Types

Select...

Article4

Relationship

Self Cite0

Independent4

Authors

Journals

Cited by 4 publications

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Mechanisms of defibrillation

Walcott

Ideker

1995

Journal of Electrocardiology

View full text Add to dashboard Cite

Electrical shock has been the one effective treatment for ventricular fibrillation for several decades. With the advancement of electrical and optical mapping techniques, histology, and computer modeling, the mechanisms responsible for defibrillation are now coming to light. In this review, we discuss recent work that demonstrates the various mechanisms responsible for defibrillation. On the cellular level, membrane depolarization and electroporation affect defibrillation outcome. Cell bundles and collagenous septae are secondary sources and cause virtual electrodes at sites far from shocking electrodes. On the whole-heart level, shock field gradient and critical points determine whether a shock is successful or whether reentry causes initiation and continuation of fibrillation.

show abstract

Mechanisms of defibrillation

Walcott

Ideker

1995

Journal of Electrocardiology

View full text Add to dashboard Cite

show abstract

Estimating defibrillation efficacy using combined upper limit of vulnerability and defibrillation testing

Malkin

Pilkington²,

Ideker³

1996

IEEE Trans. Biomed. Eng.

View full text Add to dashboard Cite

It is frequently necessary, both clinically and in the laboratory, to estimate how strong a stimulus is required to defibrillate. Current techniques for forming such estimates require the repeated induction of ventricular fibrillation (VF) and subsequent attempts at defibrillation (DF testing). DF testing can be time consuming and in the operating room may increase the patient risks. A novel scheme is presented which combines DF testing with upper limit of vulnerability (ULV) testing. ULV testing is a relatively safe procedure which yields data well correlated with defibrillation efficacy. A Bayesian statistical model of combined ULV/DF testing is presented which is both powerful and concise. The model is used in two examples to design minimum rms error protocols and estimators for the DF95 (the stimulus strength which defibrillates 95% of the time). A simulation for humans of one example solution shows that a single VF episode of combined ULV/DF testing (rms error = 23% of the mean DF95) is better than two VF episodes with DF testing alone (25%). The simulation results for a second example are directly compared with laboratory results from six pigs, showing a less than 1.0% average difference between the simulated and measured rms errors.

show abstract

High and Low Strength Nonsynchronized Shocks Given During Canine Ventricular Tachycardia

McClelland

Daubert

Kavanagh

et al. 1992

Pacing Clinical Electrophis

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

The correlation of the defibrillation threshhold and the upper limit of vulnerability using catheter-patch defibrillating electrodes

Cited by 4 publications

References 0 publications

Mechanisms of defibrillation

Mechanisms of defibrillation

Estimating defibrillation efficacy using combined upper limit of vulnerability and defibrillation testing

High and Low Strength Nonsynchronized Shocks Given During Canine Ventricular Tachycardia

Contact Info

Product

Resources

About