The Correlations of Disease Activity, Socioeconomic Status, Quality of Life, and Depression/Anxiety in Chinese Patients with Systemic Lupus Erythematosus

Shen, Biyu; Tan, Wei; Feng, Guoliang; He, Yan; Liu, Jinwei; Chen, Weijun; Huang, Xiaoqin; Da, Zhanyun; Xu, Xujuan; Liu, Hong; Gu, Zhifeng

doi:10.1155/2013/270878

Cited by 62 publications

(79 citation statements)

References 26 publications

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“…A handful of studies reported higher depression prevalence in individuals with SLE as compared to those without SLE [119,121,127]. A few studies estimated the prevalence of depression at 13% [115] and 60% [117] among adults with SLE.…”

Section: Prevalence Of Depression Among Individuals With and Withomentioning

confidence: 99%

Healthcare burden of depression in adults with arthritis

Sambamoorthi

Shah

Zhao

2017

Expert Review of Pharmacoeconomics & Outcomes Research

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Introduction Arthritis and depression are two of the top disabling conditions. When arthritis and depression exist in the same individual, they can interact with each other negatively and pose a significant healthcare burden on the patients, their families, payers, healthcare systems, and society as a whole. Areas covered The primary objective of this review is to summarize, identify knowledge gaps and discuss the challenges in estimating the healthcare burden of depression among individuals with arthritis. Electronic literature searches were performed on PubMed, Embase, EBSCOhost, Scopus, the Cochrane Library, and Google Scholar to identify relevant studies. Expert Commentary Our review revealed that the prevalence of depression varied depending on the definition of depression, type of arthritis, tools and threshold points used to identify depression, and the country of residence. Depression exacerbated arthritis-related complications as well as pain and was associated with poor health-related quality of life, disability, mortality, and high financial burden. There were significant knowledge gaps in estimates of incident depression rates, depression attributable disability, and healthcare utilization, direct and indirect healthcare costs among individuals with arthritis.

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Section: Prevalence Of Depression Among Individuals With and Withomentioning

confidence: 99%

Healthcare burden of depression in adults with arthritis

Sambamoorthi

Shah

Zhao

2017

Expert Review of Pharmacoeconomics & Outcomes Research

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“…12 With greater understanding of the interaction between pregnancy and SLE, as well as cooperation among physicians who provide care for such patients, the maternal and infant prognosis has greatly improved. 13,14 However, some patients still have a poor prognosis, or even die of worsening SLE.…”

Section: Discussionmentioning

confidence: 99%

Prognosis in Pregnant Females With Systemic Lupus Erythematosus

Liu

Zhou

2017

Arch Rheumatol

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Objectives:This study aims to analyze the relationship between pregnancy and lupus, and explore the risk factors that adversely affect maternal and infant outcomes. Patients and methods:The pregnancy outcomes in 112 pregnant females (mean age 24.3±2.8 years; range 20 to 35 years) with systemic lupus erythematosus (SLE) were retrospectively analyzed. Pregnancy outcomes before and after pregnancy were compared, and the associations with lupus nephritis, positive anti-Ro/SSA antibody, positive La/SSB antibody, complement 3 and complement 4, high blood pressure, positive anticardiolipin (aCL) antibody, Raynaud's phenomenon, and lupus recurrence were evaluated. Factors contributing to adverse outcomes were analyzed using multinomial logistic regression. Results: The live birth rate in females diagnosed with SLE before a pregnancy was higher than that in females diagnosed with SLE after a pregnancy. The fetal mortality rate in females diagnosed with SLE after a pregnancy was higher than that in females diagnosed with SLE before a pregnancy. However, the abortion rate in females diagnosed with SLE before a pregnancy was also significantly higher than that in females diagnosed with SLE after a pregnancy. The incidence of preterm birth in females diagnosed with SLE after a pregnancy was higher than that in females diagnosed with SLE after a pregnancy. Preterm birth was more likely to occur in females positive for Ro/SSA antibody. Patients with hypertension and Raynaud's phenomenon had a higher risk of intrauterine growth retardation. In addition, the presence of aCL antibody was associated with pregnancy loss. Multinomial logistic regression analysis showed that many factors might be associated with adverse pregnancy outcomes, including lupus nephritis, positive Ro/SSA antibody, positive La/SSB antibody, complement 3 and complement 4, positive aCL antibody, lupus recurrence, hypertension, and Raynaud's phenomenon. Conclusion: Lupus nephritis, Ro/SSA antibody, aCL antibody, hypertension, Raynaud's phenomenon, and lupus recurrence are important factors associated with adverse pregnancy outcomes.

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“…O nível de escolaridade das nossas participantes foi baixo, o que coloca em alerta a rede de cuidado, posto que estudos, realizados com pacientes chineses acometidos pelo LES, encontraram correlação significativa entre baixa escolaridade e sintomas de ansiedade e depressão (Mok, Chan, Cheung, & Yip, 2014;Shen et al, 2013). A escolaridade também foi associada à maior atividade da doença (Pons-Estel et al, 2004) e a adesão ao tratamento (Maldaner, Beuter, Brondani, Budó & Pauletto, 2008).…”

Section: Discussionunclassified

“…Quanto a esse dado, pesquisas apontam que índices socioeconômicos baixos estão associados a pior estado da doença, elevada morbidez psiquiátrica e alta mortalidade (Lorant et al, 2003). Somado a isso, estudos também mostram que o baixo nível socioeconômico está associado a uma menor qualidade de vida (Shen et al, 2013), a alta atividade da doença (Alarcón et al, 2006) e relacionado a danos cumulativos (Pons-Estel et al, 2004).…”

Section: Discussionunclassified

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Women With Sle, Depressive Symptoms and Social Support

Santos

Vilar

Maia

2017

Psic., Saúde & Doenças

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RESUMO:O Lúpus Eritematoso Sistêmico (LES) é uma doença autoimune crônica, rara, multissistêmica. Pesquisas apontam que o LES pode acarretar danos importantes no âmbito psicológico. Elas também sugerem que o apoio social desempenha um papel importante no desenvolvimento de estratégias de enfrentamento, na gestão do LES e na depressão. Assim, este estudo tem como objetivo geral verificar a associação entre sintomas depressivos e apoio social percebido em pacientes com LES. Utilizou-se um questionário sociodemográfico, o Inventário de Depressão de Beck e a Escala de Apoio Social Percebido. Participaram 79 mulheres, com média de idade de 35,7 anos. Destas, 55,7% eram casadas. Apenas 7,59% haviam terminado o ensino superior 40,51% ainda não finalizaram o ensino médio. 89,87% tinha renda abaixo de três salários mínimos e 89,87% praticavam alguma religião. 53,17% apresentaram níveis de sintomas depressivos de leve a grave. Quando se verificou a percepção de apoio social, os resultados mostraram níveis altos pelas participantes do estudo. Encontrouse também moderada correlação entre sintomas depressivos e apoio social (r=-0,45, p>0,001) de modo que quanto maior a frequência de apoio menor os escores de depressão. Esses achados são relevantes porque sintomas depressivos nos pacientes com LES têm um caráter multicausal e multifatorial e podem permanecer despercebidos, pois muitos deles se confundem com as manifestações da doença. Eles também corroboram com outros estudos, os quais não apenas confirmam o papel preditivo do apoio social nos aspectos físicos, mas também psicológicos. Palavras-chave: Lúpus; Mulheres, Depressão, Psicologia da Saúde ___________________________________________________________________________ WOMEN WITH SLE, DEPRESSIVE SYMPTOMS AND SOCIAL SUPPORTABSTRACT: Systemic Lupus Erythematosus (SLE) is a chronic, rare, multisystem autoimmune disease. Researches indicates that SLE can cause significant damage to the psychological realm (Carr et al., 2011;Kulczycka et al., 2009). They also suggest that social support plays an important role in the development of coping strategies, in SLE management and depression. This study has as main objective verify the association between depressive symptoms and perceived social support in patients with SLE. We used a sociodemographic questionnaire, the Beck Depression Scale, and the Perceived Social Support Scale. Campus Universitário -Lagoa Nova Natal/

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The Correlations of Disease Activity, Socioeconomic Status, Quality of Life, and Depression/Anxiety in Chinese Patients with Systemic Lupus Erythematosus

Cited by 62 publications

References 26 publications

Healthcare burden of depression in adults with arthritis

Healthcare burden of depression in adults with arthritis

Prognosis in Pregnant Females With Systemic Lupus Erythematosus

Women With Sle, Depressive Symptoms and Social Support

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