The cost comparison of rhythm and rate control strategies in persistent atrial fibrillation

A Review of the Cost of Atrial Fibrillation

“…Based on self-administered patient questionnaires, non-AF treatment costs may have been included. The How to Treat Chronic Atrial Fibrillation (HOT CAFÉ) was a smaller multicenter RCT in Poland with 205 enrolled patients who were assigned to rhythm-or rate-control treatment arms [29]. Oneyear costs were based on utilization data collected during follow-up visits and using prices reported from the specific study sites where patients were treated.…”

Cost of Illness and Drivers of Cost in Atrial Fibrillation in Sweden and Germany

“…anticoagulation and antiarrhythmic pharmacotherapy) based on either clinical trials or on decision-analytic modelling. [10][11][12][13] Commonly, these studies have been based on resource use and cost data collected within clinical trials with predefined inclusion and exclusion criteria rather than from cross-sectional samples from general real-life situations, or on estimates of resource use by expert opinion.…”

Systematic Review and Meta-analysis of the Efficacy of Cardioversion by Vernakalant and Comparators in Patients with Atrial Fibrillation

“…Rhythm control is recommended for younger patients with recent-onset or paroxysmal AF and those with shorter duration AF (≤ 48 h) [6,9]. Although existing evidence does not show one approach to be clearly superior to the other [10][11][12][13][14][15], in AF patients with distressing symptoms and/or seriously compromised cardiac function, it is of particular interest that cardioversion be achieved rapidly [5][6][7][8]16], as delayed cardioversion may worsen AF-associated symptoms and promote structural remodeling of the atria [17]. While various cardioversion therapies exist, their limitations, including limited use in certain comorbid patients, drug-drug interactions, and slow cardioversion rates, highlight the need for new treatments that are safer, more effective, and more timely in action [6,[18][19][20][21][22][23][24][25][26][27][28].…”