The Cost of Atrial Fibrillation: A Systematic Review

Buja, Alessandra; Rebba, Vincenzo; Montecchio, Laura; Renzo, Giulia; Baldo, Vincenzo; Cocchio, Silvia; Ferri, Nicola; Migliore, Federico; Zorzi, Alessandro; Collins, Brendan; Amrouch, Cheïma; De Smedt, Delphine; Kypridemos, Christodoulos; Petrovic, Mirko; O’Flaherty, Martin; Lip, Gregory Y.H.

doi:10.1016/j.jval.2023.12.015

Cited by 6 publications

(1 citation statement)

References 56 publications

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“…In addition, the costs that society would be willing to take into account for the calculated MSU effect were estimated. As currency, purchasing power parity dollars (PPP‐$) were used, a measure that takes into account the absolute purchasing power of the countries' currencies [ 21 ]. The corresponding amount of money was derived by multiplying the number of DALYs averted by the cost per DALY averted accepted in each country (Germany PPP‐$84.506 per DALY averted; Denmark PPP‐$94.390 per DALY averted; derived from 1.46 × GDP per capita from 2021, following Daroudi et al.…”

Section: Methodsmentioning

confidence: 99%

Potential effects of a mobile stroke unit on time to treatment and outcome in patients treated with thrombectomy or thrombolysis: A Danish–German cross‐border analysis

Bluhm,

Schramm,

Spreen‐Ledebur

et al. 2024

Euro J of Neurology

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Background and purposeA mobile stroke unit (MSU) reduces delays in stroke treatment by allowing thrombolysis on board and avoiding secondary transports. Due to the beneficial effect in comparison to conventional emergency medical services, current guidelines recommend regional evaluation of MSU implementation.MethodsIn a descriptive study, current pathways of patients requiring a secondary transport for mechanical thrombectomy were reconstructed from individual patient records within a Danish (n = 122) and an adjacent German region (n = 80). Relevant timestamps included arrival times (on site, primary hospital, thrombectomy centre) as well as the initiation of acute therapy. An optimal MSU location for each region was determined. The resulting time saving was translated into averted disability‐adjusted life years (DALYs).ResultsFor each region, the optimal MSU location required a median driving time of 35 min to a stroke patient. Time savings in the German region (median [Q1; Q3]) were 7 min (−15; 31) for thrombolysis and 35 min (15; 61) for thrombectomy. In the Danish region, the corresponding time savings were 20 min (8; 30) and 43 min (25; 66). Assuming 28 thrombectomy cases and 52 thrombolysis cases this would translate to 9.4 averted DALYs per year justifying an annual net MSU budget of $0.8M purchasing power parity dollars (PPP‐$) in the German region. In the Danish region, the MSU would avert 17.7 DALYs, justifying an annual net budget of PPP‐$1.7M.ConclusionThe effects of an MSU can be calculated from individual patient pathways and reflect differences in the hospital infrastructure between Denmark and Germany.

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Section: Methodsmentioning

confidence: 99%