The course and outcomes of complicated gallstone disease in pregnancy: Experience of a tertiary center

İlhan, Mehmet; İlhan, Gülşah; Gök, Ali Fuat Kaan; Günay, Kayıhan; Ertekın, Cemalettın

doi:10.4274/tjod.65475

Cited by 16 publications

(14 citation statements)

References 26 publications

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“…The second most common reason for surgical intervention during pregnancy in our study was adnexal pathology, including one case of pediculated leiomyoma, the third was cholecystolithiasis [17][18][19][20][21][22][23][24][25].…”

Section: Discussionmentioning

confidence: 75%

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Non-obstetric surgery during pregnancy – an eleven-year retrospective analysis

Vujić

Marsoner

Lipp-Pump

et al. 2019

BMC Pregnancy Childbirth

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Background: Diagnosis and management of non-obstetric abdominal pathologies during pregnancy are clinically challenging for both obstetricians and general surgeons. Our aim was to evaluate the outcome of pregnant patients who had undergone non-obstetric abdominal surgery. Methods: We retrospectively reviewed 76 pregnant patients who had required surgery for non-obstetric abdominal pathologies during pregnancy at our department from January 2005 to December 2015. Data were collected retrospectively from medical records as well as from our institutional perinatal database. We evaluated data for clinical presentation, perioperative management, preterm labor, and maternal and fetal outcomes. Results: The patients' mean age was 29 (interquartile range IQR 25-33) years. Indications for surgery were acute appendicitis in 63%, adnexal pathology in 11%, cholecystolithiasis in 5% and other indications in 21%; surgery was performed in an elective setting in 18% and in an emergent/urgent setting in 82%. In five cases, complications, three of them oncological, called for further surgery. Ninety-seven percent of operations were conducted under general anesthesia. Median skin-to-skin time was 50 (37-80) minutes, median in-hospital stay was 4 (3.5-6) days, and 5 % required postoperative intensive care. Preterm labor occurred in 15%, miscarriage in 7% (none of them directly related to abdominal surgery). Conclusion: Abdominal surgery for non-obstetric pathology during pregnancy can be performed safely, if mandatory, without increases in maternal and fetal pathology, miscarriage, and preterm birth rates.

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Section: Discussionmentioning

confidence: 75%

“…Symptomatic gallstone disease in pregnancy has been reported to be related to increased mortality risk for both the mother and fetus [17,20]. Cholecystolithiasis was diagnosed by using ultrasound (USG).…”

Section: Discussionmentioning

confidence: 99%

Non-obstetric surgery during pregnancy – an eleven-year retrospective analysis

Vujić

Marsoner

Lipp-Pump

et al. 2019

BMC Pregnancy Childbirth

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“…An increasing number of studies have suggested that laparoscopic surgeries are safe during pregnancy. [22,23,26,27] In our study, we tried to summarize our institution's experience on pregnant women with appendicitis, but the study has some limitations. These limitations include small sample size, retrospective design, only 30-day outcomes, and not well documented physical examination findings.…”

Section: Discussionmentioning

confidence: 99%

Laparoscopic versus open appendectomy in pregnancy: A single center experience

Gök

Soydaş²,

Bayraktar³

et al. 2018

Ulus Travma Acil Cerrahi Derg

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BACKGROUND: The aim of this study was to compare the obstetric and surgical outcomes of laparoscopic appendectomy (LA) and open appendectomy (OA) performed for pregnant women at a single center. It was the hypothesis of this study that there would be no significant difference in the results. METHODS: The medical records of 57 consecutive pregnant women who underwent an appendectomy between January 2009 and September 2018 were reviewed retrospectively. The patients were divided into 2 groups: OA and LA. The collected data included age, gestational age, diagnostic modalities used, duration of surgery, length of hospital stay, morbidity, and mortality. RESULTS: Eighteen (31%) patients underwent LA and 39 (69%) patients underwent OA. There were no significant differences in the demographic data. The duration of surgery was significantly less in the laparoscopic group (37 vs 57 minutes; p=0.005). There were no statistically significant differences in the outcomes of deep or superficial surgical site infection, length of hospital stay, pre-term delivery, or loss of the fetus. There was no mortality in either group. CONCLUSION: The results of this study suggest that LA can be a safe option for both the pregnant patient and the child. Further prospective, randomized studies with a larger group of pregnant patients with appendicitis are needed to fully determine the effects of laparoscopy in these circumstances.

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“…Gallstone pancreatitis is inflammation of the pancreas caused by blockage of the pancreatic duct by a gallstone. Complicated gallbladder disease refers to acute cholecystitis, choledocholithiasis, cholangitis, and/or gallstone pancreatitis . Uncomplicated gallbladder disease is defined as presence of gallstones without complications such as obstruction or inflammation.…”

Section: Terminologymentioning

confidence: 99%

Cholelithiasis: Presentation and Management

Littlefield

Lenahan

2019

J Midwife Womens Health

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Cholelithiasis affects approximately 15% of the US population. Rising trends in obesity and metabolic syndrome have contributed to an increase in diagnosis of cholelithiasis. There are several risk factors for cholelithiasis, both modifiable and nonmodifiable. Women are more likely to experience cholelithiasis than are men. Pregnancy, increasing parity, and obesity during pregnancy further increase the risk that a woman will develop cholelithiasis. The classic presentation of persons experiencing cholelithiasis, specifically when gallstones obstruct the common bile duct, is right upper quadrant pain of the abdomen that is often elicited upon palpation during physical examination and documented as a positive Murphy's sign. Referred pain to the right supraclavicular region and/or shoulder, nausea, and vomiting are also frequently reported by persons with cholelithiasis. Cholelithiasis can result in complications, including cholecystitis (inflammation of the gallbladder) and cholangitis (inflammation of the bile duct). Lack of physical examination findings does not rule out a diagnosis of cholelithiasis. Laboratory tests such as white blood cell count, liver enzymes, amylase, and lipase may assist the clinician in diagnosing cholelithiasis; however, ultrasonography is the gold standard for diagnosis. Management is dependent on severity and frequency of symptoms. Lifestyle and dietary modifications combined with medication management, such as use of gallstone dissolution agents, may be recommended for persons who have a single symptomatic episode. If symptoms become severe and/or are recurrent, laparoscopic cholecystectomy is recommended. It is recommended that individuals with an established diagnosis of cholelithiasis be referred to a surgeon and/or gastroenterologist within 2 weeks of initial presentation regardless of severity or frequency of symptoms.

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The course and outcomes of complicated gallstone disease in pregnancy: Experience of a tertiary center

Cited by 16 publications

References 26 publications

Non-obstetric surgery during pregnancy – an eleven-year retrospective analysis

Non-obstetric surgery during pregnancy – an eleven-year retrospective analysis

Laparoscopic versus open appendectomy in pregnancy: A single center experience

Cholelithiasis: Presentation and Management

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