The Course of Pregnancy in Women With Preeclampsia Combined With Fetal Growth Retardation

Abstract

In order to assess the course of pregnancy in women with diagnosed preeclampsia (PE) in combination with fetal growth retardation (FGR), 97 pregnant women (gestation period 20-32 weeks) with PE (average age 30.2±1.86 years) were examined, of which 48 women were with PE+FGR (main group), 49 women -with PE without FGR (comparison group). Age, gestational age, weight, parity, body mass index (BMI), the presence of somatic diseases were compared.A basic obstetric scan was performed and Dopplerography of the uterine and umbilical arteries was performed. Pregnant women aged 34-37 years were more likely to occur in the PE+FGR group (by 43.4%, p=0.068). In 12.5% of cases, women with PE+ FGR had a history of FGR more often (p=0.050). A significant difference was revealed in the average value of PI (1.48±0.23 and 0.92±0.12, respectively, in the main and comparative groups, p=0.033), RI (0.98±0.11 and 0.70±0.08, respectively, in the main and comparative groups, p=0.042) and S/D (3.38±0.10 and 2.90±0.22, respectively, in the main and the comparative group, p=0.050) in the umbilical artery. A frequent complication in both groups was placental insufficiency and the threat of premature birth. The incidence of acute respiratory diseases was 77.2% higher in patients with PE+FGR (p=0.028). The results of the study confirmed the importance of controlling fetal-placental blood flow.