2023
DOI: 10.1101/2023.05.05.23289582
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The Coviral Portal: Multi-Cohort Viral Loads and Antigen-Test Virtual Trials for COVID-19

Abstract: Background. Regulatory approval of new over-the-counter tests for infectious agents such as SARS-CoV-2 has historically required that clinical trials include diverse groups of specific patient populations, making the approval process slow and expensive. Showing that populations do not differ in their viral loads---the key factor determining test performance---could expedite the evaluation of new tests. Methods. 46,726 RT-qPCR-positive SARS-CoV-2 viral loads were annotated with patient demographics and health s… Show more

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“…And sixth, accessing clinical annotations from electronic medical records can be challenging. 33 As a result, the effect of clinical heterogeneity in AIRRseq studies in the setting of COVID-19 has been under-explored to date.…”
Section: Introductionmentioning
confidence: 99%
“…And sixth, accessing clinical annotations from electronic medical records can be challenging. 33 As a result, the effect of clinical heterogeneity in AIRRseq studies in the setting of COVID-19 has been under-explored to date.…”
Section: Introductionmentioning
confidence: 99%