The creation of geometric three-dimensional models of the inner ear based on micro computer tomography data

Poznyakovskiy, Anton A.; Zahnert, Thomas; Kalaidzidis, Yannis; Schmidt, Rolf; Fischer, Björn; Baumgart, Johannes; Yarin, Yury M.

doi:10.1016/j.heares.2008.06.008

Cited by 42 publications

(41 citation statements)

References 28 publications

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“…tion (Baker, 2008;van der Marel et al, 2014) or simply by setting manually two points (Poznyakovskiy et al, 2008;Verbist et al, 2009;Kjer et al, 2015). Escudé et al (2006) proposed maximization of dark pixel area using minimum intensity projection.…”

Section: Robust Modiolar Axis Estimationmentioning

confidence: 99%

Automated analysis of human cochlea shape variability from segmented μ CT images

Demarcy

Vandersteen

Guevara³

et al. 2017

Computerized Medical Imaging and Graphics

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The aim of this study is to define an automated and reproducible framework for cochlear anatomical analysis from high-resolution segmented images and to provide a comprehensive and objective shape variability study suitable for cochlear implant design and surgery planning. For the scala tympani (ST), the scala vestibuli (SV) and the whole cochlea, the variability of the arc lengths and the radial and longitudinal components of the lateral, central and modiolar paths are studied. The robustness of the automated cochlear coordinate system estimation is validated with synthetic and real data. Cochlear cross-sections are statistically analyzed using area, height and width measurements. The cross-section tilt angle is objectively measured and this data documents a significant feature for occurrence of surgical trauma.

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Section: Robust Modiolar Axis Estimationmentioning

confidence: 99%

Automated analysis of human cochlea shape variability from segmented μ CT images

Demarcy

Vandersteen

Guevara³

et al. 2017

Computerized Medical Imaging and Graphics

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“…2 as a function of distance from the centre of the source distribution, , for various values of and with a constant value of . The pressure drops quickly with the distance from the piston, especially for small , but the shortest distance between the RW and the BM is also only 0.2 mm in guinea pig [12]. Hence, excitation of the cochlea with a probe which covers just a part of the RW is possible by the near-field pressure in vicinity of the RW.…”

Section: Resultsmentioning

confidence: 99%

“…The near-field pressure variations will be limited to the vicinity of the RW membrane (Fig. 2), but the close spatial relationship between the RW and the BM [12] make excitation of the BM by these localised near-field pressure variations possible. Once the BM is stimulated in the vicinity of the RW, a conventional travelling wave is generated along the cochlear partition, which is supported by our recordings of the CAP latency.…”

Section: Discussionmentioning

confidence: 99%

Cochlear excitation by the near-field component during stimulation through the partially occluded round window

Weddell

Yarin

Drexl³

et al. 2015

AIP Conference Proceedings

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Abstract. The round window membrane (RW) provides pressure relief when the cochlea is excited by sound. While normal function of the RW is important for effective stimulation of the cochlea through the conventional oval window route, the cochlea can be stimulated successfully in non-conventional ways (e.g. through bone conduction, through the RW, and through perforations in the cochlea's apical turn). We report measurements of cochlear function from guinea pigs when the cochlea was stimulated at acoustic frequencies by movements of a miniature magnet which partially occluded the RW. Neural response latencies to acoustic and RW stimulation were similar and taken to indicate that both means of stimulation resulted in the generation of conventional travelling waves along the cochlear partition. It was concluded that the relatively high impedance of the ossicles, as seen from the cochlea, enabled the region of the RW not occluded by the magnet, to act as a pressure shunt during RW stimulation. We propose that travelling waves, similar to those due to acoustic far-field pressure changes, are driven by a jet-like, near-field component of a complex fluidpressure field, which is generated by the magnetically vibrated RW.

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“…This conclusion should be taken into account during the design of hearing aid devices which stimulate the cochlea through the partially occluded RW. The near-field pressure variations will be limited to the vicinity of the RW membrane (figure 4), but the close spatial relationship between the RW and the BM [21] makes excitation of the BM by these localized near-field pressure variations possible. Once the BM is stimulated in the vicinity of the RW, a conventional travelling wave is generated along the cochlear partition, which is supported by our CAP recordings.…”

Section: Discussionmentioning

confidence: 99%

“…The pressure drops quickly with the distance from the piston, especially for small a 1 /a 2 , but the shortest distance between the RW and the BM is also only 0.2 mm in guinea pigs [21]. Hence, excitation of the cochlea with a magnet that covers just a part of the RW is possible by the near-field pressure in the vicinity of the RW.…”

Section: ð3:10þmentioning

confidence: 96%

A novel mechanism of cochlear excitation during simultaneous stimulation and pressure relief through the round window

Weddell

Yarin

Drexl³

et al. 2014

J. R. Soc. Interface.

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The round window (RW) membrane provides pressure relief when the cochlea is excited by sound. Here, we report measurements of cochlear function from guinea pigs when the cochlea was stimulated at acoustic frequencies by movements of a miniature magnet which partially occluded the RW. Maximum cochlear sensitivity, corresponding to subnanometre magnet displacements at neural thresholds, was observed for frequencies around 20 kHz, which is similar to that for acoustic stimulation. Neural response latencies to acoustic and RW stimulation were similar and taken to indicate that both means of stimulation resulted in the generation of conventional travelling waves along the cochlear partition. It was concluded that the relatively high impedance of the ossicles, as seen from the cochlea, enabled the region of the RW not occluded by the magnet, to act as a pressure shunt during RW stimulation. We propose that travelling waves, similar to those owing to acoustic farfield pressure changes, are driven by a jet-like, near-field component of a complex pressure field, which is generated by the magnetically vibrated RW. Outcomes of research described here are theoretical and practical design principles for the development of new types of hearing aids, which use near-field, RW excitation of the cochlea.

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The creation of geometric three-dimensional models of the inner ear based on micro computer tomography data

Cited by 42 publications

References 28 publications

Automated analysis of human cochlea shape variability from segmented μ CT images

Automated analysis of human cochlea shape variability from segmented μ CT images

Cochlear excitation by the near-field component during stimulation through the partially occluded round window

A novel mechanism of cochlear excitation during simultaneous stimulation and pressure relief through the round window

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