The CT Scan Appearance of the Brain in the Normal Elderly Population: A Correlative Study

Gonzalez, Carlos F.; Lantieri, R; Nathan, Rachel

doi:10.1007/978-3-642-66959-0_39

Cited by 9 publications

(11 citation statements)

References 6 publications

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“…Unfortunately, those measures do not correlate with the indexes of neuropsychological decline in a satisfactory manner (41, 45,57,73,118,150). Even when clever procedures are used to determine ratios of ventricular areas to brain areas at the same slice level, the correlations remain tentative, at best (2, 11, 22, 32, 37, 128).…”

Section: Neuroimaging Investigation Of Alzheimer's Diseasementioning

confidence: 99%

Alzheimer's Disease

Hyman¹,

Damasio²,

Damasio³

et al. 1989

Annu. Rev. Public Health

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Section: Neuroimaging Investigation Of Alzheimer's Diseasementioning

confidence: 99%

Alzheimer's Disease

Hyman¹,

Damasio²,

Damasio³

et al. 1989

Annu. Rev. Public Health

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“…Studies on the ventricular size and the size of the sulci have previously been performed, usually with patients, medical personnel or volunteers as subjects (2,6,7,16). No study of a randomly selected population including subjects over 65 years of age has been reported earlier.…”

Section: Discussionmentioning

confidence: 99%

Computed Tomography of the Brain in Cases with Venous Vasculitis Compared with an Age-Matched Reference Group

Hannerz¹,

Bergstrand²,

Berggren³

et al. 1988

Acta Radiol

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Patients with a particular, steroid-sensitive headache and often characteristic pathology at orbital phlebography, have been suggested to suffer from venous vasculitis. Fifty such patients were examined with computed tomography (CT) of the brain. The findings were compared with those of an age-matched reference group selected at random to represent normal subjects. The CT examinations were analyzed with respect to size of lateral ventricles and signs of atrophy. In both groups, there was a significant increase of atrophy with age. There was also a significantly higher degree of atrophy in the patient group as compared with the reference group. The findings indicate that the supposedly underlying venous vasculitis is related to early aging and atrophy of the brain.

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“…CT studies of older patients using neurologic tests and geriatric rating scales have focused on CT changes related to age, 20–23 normal function, 24 dementia, 2,4,5,10,11,20,25 affective illness, 3,26–27 as well as overall prognosis and survival in those with and without CT changes 8,28 . Diagnostic distinction between dementia and depression can be a tenuous and difficult task.…”

Section: Discussionmentioning

confidence: 99%

Behavioral Correlates of Computed Tomographic (CT) Scan Changes in Older Psychiatric Patients

Swigar

Beneš

Rothman

et al. 1985

J American Geriatrics Society

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Fifty psychiatric inpatients aged 50 and over, with no hard neurologic findings, and with a variety of DSM-III diagnoses (adjustment disorder, affective illness, and dementia), were rated for behavioral and psychiatric symptoms using the Geriatric Rating Scale and the Nurse's Assessment of Global Symptomatology-Elderly. These clinical ratings were correlated with computed tomographic (CT) scan assessments of various superficial cerebral regions as well as with linear measures of ventricular size. Behavioral deficits in activities of daily living (ADL) plus an interactional variable, inability to respond to requests, were correlated with superior temporal and inferior parietal CT abnormalities, particularly on the left side. Suspiciousness and peculiar thinking, mood lability and irritability, as well as impaired memory with confusion, perplexity, and disorientation were also associated with atrophy in these same regions. Prefrontal area defects correlated with mood lability and deficits in visual-interactional responsiveness. Statistically controlling for effects of age and alcohol abuse did not alter the basic nature of these results. Regional cerebral specialization in relation to these results are discussed using concepts developed by Luria.

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The CT Scan Appearance of the Brain in the Normal Elderly Population: A Correlative Study

Cited by 9 publications

References 6 publications

Alzheimer's Disease

Alzheimer's Disease

Computed Tomography of the Brain in Cases with Venous Vasculitis Compared with an Age-Matched Reference Group

Behavioral Correlates of Computed Tomographic (CT) Scan Changes in Older Psychiatric Patients

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