The current applications of nano and biomaterials in drug delivery of dental implant

Abstract

Background and aim Dental implantology has revolutionized oral rehabilitation, offering a sophisticated solution for restoring missing teeth. Despite advancements, issues like infection, inflammation, and osseointegration persist. Nano and biomaterials, with their unique properties, present promising opportunities for enhancing dental implant therapies by improving drug delivery systems. This review discussed the current applications of nano and biomaterials in drug delivery for dental implants. Method A literature review examined recent studies and advancements in nano and biomaterials for drug delivery in dental implantology. Various materials, including nanoparticles, biocompatible polymers, and bioactive coatings, were reviewed for their efficacy in controlled drug release, antimicrobial properties, and promotion of osseointegration. Results Nano and biomaterials exhibit considerable potential in improving drug delivery for dental implants. Nanostructured drug carriers demonstrate enhanced therapeutic efficacy, sustained release profiles, and improved biocompatibility. Furthermore, bioactive coatings contribute to better osseointegration and reduced risks of infections. Conclusion Integrating current nano and biomaterials in drug delivery for dental implants holds promise for advancing clinical outcomes. Enhanced drug delivery systems can mitigate complications associated with dental implant procedures, offering improved infection control, reduced inflammation, and optimized osseointegration.

Challenges and Pitfalls of Research Designs Involving Magnesium-Based Biomaterials: An Overview

“…In more recent research, a notable paradigm shift has become evident: inert implants are now subjected to chemical treatments to enhance their biological activity. There is a growing interest in the use of resorbable materials and corrodible metals for biomedical applications, where controlled biodegradation could provide clinical benefits [ 125 , 126 ]. These materials are intended to release chemical substances and metal ions in a controlled manner within the body.…”