The current economic burden of illness of osteoporosis in Canada

Hopkins, Robert; Burke, Natasha; Keyserlingk, Camilla von; Leslie, William D.; Morin, Suzanne N; Adachi, Jonathan D.; Παπαϊωάννου, Αλεξάνδρα; Bessette, Louis; Brown, Jacques P.; Pericleous, L.; Tarride, Jean‐Éric

doi:10.1007/s00198-016-3631-6

Cited by 109 publications

(64 citation statements)

References 11 publications

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“…In Canada, of the approximate 30 000 hip fractures that occur annually, 70% to 90% of these are caused by osteoporosis. Hopkins et al estimate the current burden of illness of osteoporosis in Canada is double ($4.6 billion) our previous estimates ($2.3 billion) due to improved data capture of the multiple encounters and treatment and rehabilitation services that accompany the management of a hip fracture. Also, approximately 50% of older adults who lived independently before sustaining a hip fracture are unable to regain their independent lifestyle; instead, they face ongoing disability and prolonged institutionalization.…”

Section: The Hidden Burden Of Osteoporosismentioning

confidence: 96%

“…In Canada, of the approximate 30 000 hip fractures that occur annually, 70% to 90% of these are caused by osteoporosis. Hopkins et al 3…”

Section: The Hidden Burden Of Osteoporosismentioning

confidence: 99%

“…9 The strong relationship between low bone mass and risk of fracture has been well documented. 3,[10][11][12][13][14] Whereas osteoporosis in postmenopausal women is a well-recognized and extensively investigated health problem, there is a paucity of research on the effects of osteoporosis for older men. As a result, male osteoporosis remains largely underdiagnosed and undertreated.…”

Section: Estimate the Current Burden Of Illness Of Osteoporosis Inmentioning

confidence: 99%

“…Nearly three‐quarters (72%) of Canadians aged 65 and over report having at least one chronic illness and many reporting multimorbidity . Increasing rates of chronic illness, including osteoporosis, correlate with an increase in health care service utilization with older adults accounting for 50% of hospitalized patients, 85% of home care patients, and over 90% of long‐term care residents …”

Section: Introductionmentioning

confidence: 99%

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Optimizing osteoporosis care in a rural primary health care center: Findings of a research study aimed to support seniors

et al. 2019

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Background Osteoporosis is one of the most under‐diagnosed and under‐treated health conditions in Canada. This study questioned whether an invitation to self‐refer for osteoporosis risk evaluation would improve the number of patients who were tested for bone mineral density (BMD) at a rural Primary Health Care Center (PHCC). Purpose The purpose of this study is to improve osteoporosis care and decrease bone fracture risk in a population of patients 65 years of age and older. Methodology A quasi‐experimental research design was used to review screening rates of BMD testing and identified patients in this population who were at low, moderate, and high risk for developing osteoporosis. Screening rates at the PHCC were compared to screening rates at another rural PHCC in the province. Conclusion The self‐referral program for BMD testing and a nurse‐led intervention resulted in an increased number of people who were BMD tested at the study PHCC compared with the control PHCC, and identified more male patients 65 years of age and older who were at risk for osteoporosis and bone fractures. Recommendations suggest future research in other provincial PHCCs that may encourage self‐referral programs for BMD testing and improved osteoporosis care for patients 65 years of age and older.

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Section: The Hidden Burden Of Osteoporosismentioning

confidence: 96%

“…In Canada, of the approximate 30 000 hip fractures that occur annually, 70% to 90% of these are caused by osteoporosis. Hopkins et al 3…”

Section: The Hidden Burden Of Osteoporosismentioning

confidence: 99%

Section: Estimate the Current Burden Of Illness Of Osteoporosis Inmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Optimizing osteoporosis care in a rural primary health care center: Findings of a research study aimed to support seniors

et al. 2019

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“…In Italy, the direct hospitalization costs for the treatment of patients with fragility fractures over the age of 65 were almost 400 € million in 2002, with a 15% increase in the following three years [11]. The socio-economic burden of fragility fractures is not unique to Europe, but affects all countries with an aging population, such as Australia [12], Canada [13], China [14], and Taiwan [7]. On average, patients suffering from osteoporotic fractures increase their risk of exposure to a second fracture by 86%.…”

Section: Introductionmentioning

confidence: 99%

Fragility Fracture Prevention—Implementing a Fracture Liaison Service in a High Volume Orthopedic Hospital

Pennestrì

Corbetta

Favero

et al. 2019

IJERPH

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Fragility fractures pose a serious threat to patient health, quality of life, and healthcare sustainability. In order to reduce their clinical, social, and economic burden, a Fracture Liaison Service (FLS) was introduced in a high volume orthopedic hospital in 2017. The purpose of this retrospective observational study is to describe the FLS protocol, introduce its preliminary outcomes, and provide an early evaluation in light of international guidelines and recommendations. All the performances suggested by the International Osteoporosis Foundation (IOF) are provided under the same institution by which a patient is admitted for surgery. Clinical indicators from patient history and administrative indicators from the hospital database have been used to estimate the spread of fragility fracture prevention and the degree of patient compliance to these programs. The research included 403 patients. Although, almost 1/3 were admitted for the second fragility fracture, only half received anti-osteoporotic treatment before it. The degree of prevention was even lower in the case of patients admitted for the first fragility fracture. The risk of being affected by a secondary fracture was seven times higher when patients did not attend any follow-up or diagnostic exam. In order to identify the main determinants of compliance with FLS and perform a cost-effectiveness analysis on a larger sample, it is fundamental to integrate data from different providers.

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Association Between Age at Puberty and Bone Accrual From 10 to 25 Years of Age

et al. 2019

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IMPORTANCE Bone health in early life is thought to influence the risk of osteoporosis in later life. OBJECTIVE To examine whether puberty timing is associated with bone mineral density accrual up to adulthood. DESIGN, SETTING, AND PARTICIPANTS This cohort study used data from the Avon Longitudinal Study of Parents and Children, a prospective population-based birth cohort initiated in 1991 to 1992 in southwest England. The participants were 6389 healthy British people who underwent regular follow-up, including up to 6 repeated bone density scans from ages 10 to 25 years. Data analysis was performed from June 2018 to June 2019. EXPOSURES Age at puberty from estimated age at peak height velocity (years). MAIN OUTCOMES AND MEASURES Gains per year in whole-body bone mineral density (grams per square centimeter), assessed by dual-energy x-ray absorptiometry at ages 10, 12, 14, 16, 18, and 25 years and modeled using linear splines. RESULTS A total of 6389 participants (3196 [50.0%] female) were included. The mean (SD) age at peak height velocity was 13.5 (0.9) years for male participants and 11.6 (0.8) years for female participants. Male participants gained bone mineral density at faster rates than did female participants, with the greatest gains in both male participants (0.139 g/cm 2 /y; 95% CI, 0.127-0.151 g/cm 2 /y) and female participants (0.106 g/cm 2 /y; 95% CI, 0.098-0.114 g/cm 2 /y) observed between the year before and 2 years after peak height velocity. When aligned by chronological age, per 1-year older age at puberty was associated with faster subsequent gains in bone mineral density; the magnitudes of faster gains were greatest between ages 14 and 16 years in both male participants (0.013 g/cm 2 /y; 95% CI, 0.011-0.015 g/cm 2 /y) and female participants (0.014 g/cm 2 /y; 95% CI, 0.014-0.015 g/cm 2 /y), were greater in male participants (0.011 g/cm 2 /y; 95% CI, 0.010-0.013 g/cm 2 /y) than in female participants (0.003 g/cm 2 /y; 95% CI, 0.003-0.004 g/cm 2 /y) between ages 16 and 18 years, and were least in both male participants (0.002 g/cm 2 /y; 95% CI, 0.001-0.003 g/cm 2 /y) and female participants (0.000 g/cm 2 /y; 95% CI, −0.001 to 0.000 g/cm 2 /y) between ages 18 and 25 years. Despite faster gains, older age at puberty was associated with persistently lower bone mineral density, changing from 0.050 g/cm 2 (95% CI, −0.056 to −0.045 g/cm 2) lower at age 14 years to 0.047 g/cm 2 (95% CI, −0.051 to −0.043 g/cm 2) lower at age 25 years in male participants and from 0.044 g/cm 2 (95% CI, −0.046 to −0.041 g/cm 2) to 0.034 g/cm 2 (95% CI, −0.036 to −0.032 g/cm 2) lower at the same ages in female participants. (continued) Key Points Question Is puberty timing associated with growth-related bone accrual up to adulthood? Findings In this cohort study of 6389 participants who underwent repeated bone density scans from ages 10 to 25 years, later puberty was associated with persistently lower bone mineral density, despite some catch-up during puberty. Meaning People with older pubertal age should be advised on how t...

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The current economic burden of illness of osteoporosis in Canada

Cited by 109 publications

References 11 publications

Optimizing osteoporosis care in a rural primary health care center: Findings of a research study aimed to support seniors

Optimizing osteoporosis care in a rural primary health care center: Findings of a research study aimed to support seniors

Fragility Fracture Prevention—Implementing a Fracture Liaison Service in a High Volume Orthopedic Hospital

Association Between Age at Puberty and Bone Accrual From 10 to 25 Years of Age

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