The Current Knowledge on the Pathogenesis of Tissue and Medical Device-Related Biofilm Infections

Domenico, Enea Gino Di; Oliva, Alessandra; Guembe, María

doi:10.3390/microorganisms10071259

Cited by 48 publications

(27 citation statements)

References 129 publications

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“…Infectious diseases associated with biofilms are believed to account for over 80% of chronic diseases, and conventional antibiotics are ineffective in eliminating these infections [ 35 , 36 , 37 ]. Irrespective of the location of the biofilm, bacteria found on them are resistant or tolerant to the response of the host immune system, antiseptic agents, antibiotic therapy, germicides, and disinfectants [ 38 ].…”

Section: Bacterial Biofilmsmentioning

confidence: 99%

Beyond the Risk of Biofilms: An Up-and-Coming Battleground of Bacterial Life and Potential Antibiofilm Agents

Zeineldin

Esmael

Al-Hindi

et al. 2023

Life

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Microbial pathogens and their virulence factors like biofilms are one of the major factors which influence the disease process and its outcomes. Biofilms are a complex microbial network that is produced by bacteria on any devices and/or biotic surfaces to escape harsh environmental conditions and antimicrobial effects. Due to the natural protective nature of biofilms and the associated multidrug resistance issues, researchers evaluated several natural anti-biofilm agents, including bacteriophages and their derivatives, honey, plant extracts, and surfactants for better destruction of biofilm and planktonic cells. This review discusses some of these natural agents that are being put into practice to prevent biofilm formation. In addition, we highlight bacterial biofilm formation and the mechanism of resistance to antibiotics.

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Section: Bacterial Biofilmsmentioning

confidence: 99%

Beyond the Risk of Biofilms: An Up-and-Coming Battleground of Bacterial Life and Potential Antibiofilm Agents

Zeineldin

Esmael

Al-Hindi

et al. 2023

Life

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“…Therefore, it has been amply described that the bacterial biofilm contributes to persistent chronic infections (Sharma et al, 2019). Several studies in humans indicate that chronic infections are related to the presence of biofilm on several internal organs including the skin or mucosal surfaces of the respiratory and digestive tract (Di Domenico et al, 2022). In fish, some studies have focused on adhesion and colonization of tissues by several pathogens such as Flavobacterium columnare (Decostere et al, 1999;Staroscik & Nelson, 2008), Streptococcus agalactiae associated with chronic meningoencephalitis in tilapia (Isiaku et al, 2017), and also P. salmonis, which forms microcolony-like aggregations in skeletal muscle of O. mykiss (Smith et al, 2015).…”

Section: Growth Phasementioning

confidence: 99%

Effect of florfenicol on Piscirickettsia salmonis biofilm formed in materials used in salmonid nets, nylon and high‐density polyethylene

Oliver,

Ruiz,

Vidal

et al. 2023

Journal of Fish Diseases

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Piscirickettsiosis is the most prevalent bacterial disease affecting seawater salmon in Chilean salmon industry. Antibiotic therapy is the first alternative to counteract infections caused by Piscirickettsia salmonis. The presence of bacterial biofilms on materials commonly used in salmon farming may be critical for understanding the bacterial persistence in the environment. In the present study, the CDC Biofilm Reactor® was used to investigate the effect of sub‐ and over‐MIC of florfenicol on both the pre‐formed biofilm and the biofilm formation by P. salmonis under the antibiotic stimuli on Nylon and high‐density polyethylene (HDPE) surfaces. This study demonstrated that FLO, at sub‐ and over‐MIC doses, decreases biofilm‐embedded live bacteria in the P. salmonis isolates evaluated. However, it was shown that in the P. salmonis Ps007 strain the presence of sub‐MIC of FLO reduced its biofilm formation on HDPE surfaces; however, biofilm persists on Nylon surfaces. These results demonstrated that P. salmonis isolates behave differently against FLO and also, depending on the surface materials. Therefore, it remains a challenge to find an effective strategy to control the biofilm formation of P. salmonis, and certainly other marine pathogens that affect the sustainability of the Chilean salmon industry.

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“…Surface adhesion and biofilm formation are central elements for bacterial persistence on the skin surface 23 . Given their significance, the capacity of L. crispatus P17631 and L. paracasei I1688 to adhere to surfaces and form biofilms was investigated using the BRT (Fig.…”

Section: Lactobacillus Crispatus P17631 and Lacticaseibacillus Paraca...mentioning

confidence: 99%

Probiotic-enriched oily suspension in modulating skin microbiome and treating seborrheic dermatitis

Domenico,

Truglio,

Sivori

et al. 2023

Preprint

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Seborrheic dermatitis (SD) affects 2-5% of the global population, with imbalances in the skin microbiome implicated in its development. This study assessed the impact of an oily suspension containing Lactobacillus crispatus P17631 and Lacticaseibacillus paracasei I1688 (termed EUTOPLAC) on SD symptoms and skin microbiome modulation. 25 SD patients were treated with EUTOPLAC for a week. Symptom severity and skin microbiome changes were measured at the start of the treatment (T0), after seven days (T8), and three weeks post-treatment (T28). Results indicated symptom improvement post-EUTOPLAC, with notable reductions in the Malassezia genus. Concurrently, bacterial shifts were observed, including a decrease in Staphylococcus and an increase in Lactobacillus and Lacticaseibacillus. Network analysis highlighted post-EUTOPLAC instability in fungal and bacterial interactions, with increased negative correlations between Malassezia and Lactobacillus and Lacticaseibacillus genera. The study suggests EUTOPLAC's potential as a targeted SD treatment, reducing symptoms and modulating the microbiome composition.

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The Current Knowledge on the Pathogenesis of Tissue and Medical Device-Related Biofilm Infections

Cited by 48 publications

References 129 publications

Beyond the Risk of Biofilms: An Up-and-Coming Battleground of Bacterial Life and Potential Antibiofilm Agents

Beyond the Risk of Biofilms: An Up-and-Coming Battleground of Bacterial Life and Potential Antibiofilm Agents

Effect of florfenicol on Piscirickettsia salmonis biofilm formed in materials used in salmonid nets, nylon and high‐density polyethylene

Probiotic-enriched oily suspension in modulating skin microbiome and treating seborrheic dermatitis

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