2018
DOI: 10.1016/j.ejso.2018.07.003
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The current practice of cytoreductive surgery and HIPEC for colorectal peritoneal metastases: Results of a worldwide web-based survey of the Peritoneal Surface Oncology Group International (PSOGI)

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Cited by 124 publications
(98 citation statements)
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“…Retrospective comparisons between oxaliplatin and mitomycin C (MMC), the two drugs most commonly used in HIPEC for PMs from colorectal cancer, generated contradictory results. As a consequence, there is currently no consensus on the choice of chemotherapy, the dose administered or the duration of perfusion. Regardless of the chemotherapy drug used in HIPEC, recurrence rates after CRS–HIPEC are high and more than half of patients experience disease recurrence within 2 years.…”
Section: Introductionmentioning
confidence: 99%
“…Retrospective comparisons between oxaliplatin and mitomycin C (MMC), the two drugs most commonly used in HIPEC for PMs from colorectal cancer, generated contradictory results. As a consequence, there is currently no consensus on the choice of chemotherapy, the dose administered or the duration of perfusion. Regardless of the chemotherapy drug used in HIPEC, recurrence rates after CRS–HIPEC are high and more than half of patients experience disease recurrence within 2 years.…”
Section: Introductionmentioning
confidence: 99%
“…In the last decades, the therapeutic strategy for colorectal peritoneal surface malignancy (PSM) has changed considerably from a palliative approach to an approach with curative intent by the introduction of cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal perioperative chemotherapy (HIPEC) . This combined treatment modality has resulted in significant survival improvements with a median overall survival of 41.7 months and should now be considered standard of care for colorectal PSM (results presented at the American Society of Clinical Oncology [ASCO] annual meeting in Chicago) .…”
Section: Introductionmentioning
confidence: 99%
“…Although, there is now a clearly defined standardization of CRS procedures, based on the work of Sugarbaker et al, there is still a large variety in HIPEC treatment modalities used in current clinical practice. Methodological variations to be considered are: technique (open vs closed), normothermic vs hyperthermic chemotherapy, drug selection, drug dose, exposure time, and dosing regimen …”
Section: Introductionmentioning
confidence: 99%
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“…They are often chemo-resistant, associated with other peritoneal metastases, and confer a worse prognosis [35,36]. Ovarian metastases from CRC are peritoneal disease and therefore should be treated with CRS and HIPEC [37,38]. A laparoscopy may be performed to evaluate PCI as other peritoneal deposits may be present.…”
Section: Discussionmentioning
confidence: 99%