Based on materials from resource studies 2000–2021 a review of the dynamics of stocks and biological indicators of the main commercial fish species of the Kuibyshev reservoir was prepared. The data on their development by trade are given. The reserves of biological resources of this reservoir are shown. Recommendations on rational use are given: it is proposed to increase the catch of roach, silver bream, perch, crucian carp, blue breeze and other underutilized species, which will make it possible to obtain an additional 400 tons of high-quality fish.