The current status of low level laser therapy in detistry. Part 2. Hard tissue applications

Walsh, Laurence J.

doi:10.1111/j.1834-7819.1997.tb00134.x

Cited by 179 publications

(83 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…7,8 In recent studies, the Ga-Al-As type of diode lasers has been shown to be more effective in biostimulation than He-Ne lasers due to the higher penetration ability into the deep tissues. 9 The dose-dependent…”

Section: Introductionmentioning

confidence: 99%

The efficacy of low-level 940 nm laser therapy with different energy intensities on bone healing

et al. 2017

View full text Add to dashboard Cite

The aim of this study was to evaluate the efficacy of low-level 940 nm laser therapy with energy intensities of 5, 10 and 20 J/cm 2 on bone healing in an animal model. A total of 48 female adult Wistar rats underwent surgery to create bone defects in the right tibias. Low-level laser therapy (LLLT) was applied immediately after surgery and on post-operative days 2, 4, 6, 8, 10 and 12 in three study groups with energy intensities of 5 J/cm 2 , 10 J/cm 2 and 20 J/cm 2 using a 940 nm Gallium-Aluminium-Arsenide (Ga-Al-As) laser, while one control group underwent only the tibia defect surgery. All animals were sacrificed 4 or 8 weeks post-surgery. Fibroblasts, osteoblasts, osteocytes, osteoclasts and newly formed vessels were evaluated by a histological examination. No significant change was observed in the number of osteocytes, osteoblasts, osteoclasts and newly formed vessels at either time period across all laser groups. Although LLLT with the 10 J/cm 2 energy density increased fibroblast activity at the 4th week in comparison with the 5 and 20 J/cm 2 groups, no significant change was observed between the laser groups and the control group. These results indicate that low-level 940 nm laser with different energy intensities may not have marked effects on the bone healing process in both phases of bone formation.

show abstract

Section: Introductionmentioning

confidence: 99%

The efficacy of low-level 940 nm laser therapy with different energy intensities on bone healing

et al. 2017

View full text Add to dashboard Cite

show abstract

“…At low doses (2 J/cm 2 ) phototherapy stimulates fibroblast proliferation while higher doses (16 J/cm 2 ) are suppressive, pointing to the dose dependence of biological responses after light exposure. Low energy laser irradiation alters the cellular function by influencing protein synthesis, cell growth and differentiation, cell motility, membrane potential and binding affinities, neurotransmitter release, ATP synthesis, and prostaglandin synthesis [23,24].…”

Section: Introductionmentioning

confidence: 99%

The role of laser fluence in cell viability, proliferation, and membrane integrity of wounded human skin fibroblasts following helium‐neon laser irradiation

2006

View full text Add to dashboard Cite

Background: In medicine, lasers have been used predominantly for applications, which are broadly termed low level laser therapy (LLLT), phototherapy or photobiomodulation. This study aimed to establish cellular responses to Helium-Neon (632.8 nm) laser irradiation using different laser fluences (0.5, 2.5, 5, 10, and 16 J/cm 2 ) with a single exposure on 2 consecutive days on normal and wounded human skin fibroblasts. Materials and Methods: Changes in normal and wounded fibroblast cell morphology were evaluated by light microscopy. Changes following laser irradiation were evaluated by assessing the mitochondrial activity using adenosine triphosphate (ATP) luminescence, cell proliferation using neutral red and an alkaline phosphatase (ALP) activity assay, membrane integrity using lactate dehydrogenase (LDH), and percentage cytotoxicity and DNA damage using the Comet assay. Results: Morphologically, wounded cells exposed to 5 J/ cm 2 migrate rapidly across the wound margin indicating a stimulatory or positive influence of phototherapy. A dose of 5 J/cm 2 has a stimulatory influence on wounded fibroblasts with an increase in cell proliferation and cell viability without adversely increasing the amount of cellular and molecular damage. Higher doses (10 and 16 J/cm 2 ) were characterized by a decrease in cell viability and cell proliferation with a significant amount of damage to the cell membrane and DNA. Conclusions: Results show that 5 J/cm 2 stimulates mitochondrial activity, which leads to normalization of cell function and ultimately stimulates cell proliferation and migration of wounded fibroblasts to accelerate wound closure. Laser irradiation can modify cellular processes in a dose or fluence (J/cm 2 ) dependent manner. Lasers Surg.

show abstract

“…Both the CO2 and Nd:YAG lasers have a thermal effect on both soft and hard tissues. Yet, the Er:YAG laser is more efficient in absorption, both in water and in hydroxyapatite and, for that, has been reported to have less of a thermal effect on dental hard tissue [93,94].…”

Section: Dental Applicationsmentioning

confidence: 99%

New Trends in Dental Biomechanics with Photonics Technologies

et al. 2015

View full text Add to dashboard Cite

show abstract

The current status of low level laser therapy in detistry. Part 2. Hard tissue applications

Cited by 179 publications

References 27 publications

The efficacy of low-level 940 nm laser therapy with different energy intensities on bone healing

The efficacy of low-level 940 nm laser therapy with different energy intensities on bone healing

The role of laser fluence in cell viability, proliferation, and membrane integrity of wounded human skin fibroblasts following helium‐neon laser irradiation

New Trends in Dental Biomechanics with Photonics Technologies

Contact Info

Product

Resources

About