The cut-off points of the Depression and Somatic Symptoms Scale and the Hospital Anxiety and Depression Scale in detecting non-full remission and a current major depressive episode

Hung, Ching‐I; Liu, Chia Yih; Wang, Shuu Jiun; Yao, Yi Chun; Yang, Ching Hui

doi:10.3109/13651501.2011.617456

Cited by 41 publications

(32 citation statements)

References 21 publications

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“…We reanalysed the HAM‐D 17 data from a cross‐sectional study of depression scales (Hung, Liu, Wang, Yao, & Yang, ). The sample consisted of 214 adult psychiatric outpatients (mean age [SD]: 38.3 [10.5] years; 135 [63.1%] females).…”

Section: Methodsmentioning

confidence: 99%

Psychometric evaluation of a 6‐item Chinese version of the Hamilton Depression Rating Scale: Mokken scaling and item analysis

Lee

Liu

Hung

2017

Asia-Pacific Psychiatry

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Section: Methodsmentioning

confidence: 99%

Psychometric evaluation of a 6‐item Chinese version of the Hamilton Depression Rating Scale: Mokken scaling and item analysis

Lee

Liu

Hung

2017

Asia-Pacific Psychiatry

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“…The four symptoms were considered as physical symptoms for consistency with past studies. The reliability and validity of the DSSS have been reported [17,18,19]. The HADS includes seven items for anxiety and seven for depression, but no items for somatic symptoms.…”

Section: Methodsmentioning

confidence: 99%

Residual Symptoms Related to Physical and Panic Symptoms at Baseline Predict Remission of Depression at Follow-Up

et al. 2013

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Aims: The study aimed to investigate whether common residual symptoms at baseline were able to predict full remission of depression at 6-month and 2-year follow-up examinations in patients with major depressive disorder (MDD). Methods: This study enrolled 135 outpatients with MDD. The depression (DS) and somatic subscales (SS) of the Depression and Somatic Symptoms Scale and the depression and anxiety (HADS-A) subscales of the Hospital Anxiety and Depression Scale were used to investigate residual symptoms, which were divided into the common residual part (CRP) and the other residual part (ORP). Multivariate logistic regression was used to compare the ability to predict full remission between the CRP and ORP scores at baseline. Results: One hundred and nineteen and 106 outpatients completed the two follow-up examinations. The CRP of the DS and the ORP of the SS and HADS-A at baseline had a good ability to predict full remission among patients without pharmacotherapy. The three residual parts included physical and anxiety symptoms of depression and panic symptoms. Conclusions: Physicians should pay attention to physical, anxiety, and panic symptoms, because these symptoms are related to remission of depression. Future studies should explore how these symptoms affect the prognosis of depression.

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“…A patient with an anxiety score (HADS-A) ≥ 8 is deemed to have an anxiety disorder (sensitivity, 0.89; specificity, 0.75) and a patient with a depression score (HADS-D) ≥ 8 is deemed to have a depression disorder (sensitivity, 0.80; specificity, 0.88) [18]. The validation and cut-off score of Chinese version of the HADS have been reported in previous studies [19, 20]. …”

Section: Methodsmentioning

confidence: 99%

Treatment-emergent depression and anxiety between peginterferon alpha-2a versus alpha-2b plus ribavirin for chronic hepatitis C

Wang

Chen

et al. 2016

BMC Psychiatry

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BackgroundThis study investigates differences in depression and anxiety between patients with chronic hepatitis C who are treated with peginterferon alpha-2a (PegIFN-α-2a) plus ribavirin and those who are treated with peginterferon alpha-2b (PegIFN-α-2b) plus ribavirin.MethodsIn this 24 week, non-randomized, observational, prospective study, 55 patients with chronic hepatitis C were treated with PegIFN-α-2a plus ribavirin (Group 1), and 26 patients were treated with PegIFN-α-2b plus ribavirin (Group 2). All patients underwent assessment using the Hospital Anxiety and Depression Scale (HADS) at the baseline and at weeks 4, 12 and 24. Patients with depression scores (HADS-D) ≥ 8 and anxiety scores (HADS-A) ≥ 8 were defined as having depression and anxiety, respectively. The factors that were associated with depression and anxiety during the 24 week antiviral treatment were determined.ResultsDuring the 24 week antiviral treatment, the proportion of patients with depression significantly increased over time in both groups (Group 1: p = 0.048; Group 2: p = 0.044). The proportion of patients with anxiety did not significantly change during the follow-up period in either group. Incidences of depression or anxiety did not differ significantly between Group 1 and Group 2. A history of alcohol use disorder was an independent predictor of depression at week 12 (p < 0.001) and week 24 (p < 0.001), and a poor virological response to treatment was associated with depression at week 24 (p = 0.029). Patients who had more physical comorbidities were more likely to suffer from anxiety at week 12 (p = 0.038).ConclusionsThis study did not identify significant differences in depression or anxiety between in patients with chronic hepatitis C who underwent a 24 week antiviral treatment regimen with PegIFN-α-2a plus ribavirin and those who underwent a regiment with PegIFN-α-2b plus ribavirin. Future research with larger samples and a randomized, controlled design are required to verify the findings in this study.Trial registrationThis clinical study has been registered at ClinicalTrials.gov. (Trial registration: NCT02943330).

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The cut-off points of the Depression and Somatic Symptoms Scale and the Hospital Anxiety and Depression Scale in detecting non-full remission and a current major depressive episode

Abstract: The DSSS and HADS can be used to distinguish different depressive states. The results demonstrated the discriminative validity of the DSSS and the HADS.

Cited by 41 publications

References 21 publications

Psychometric evaluation of a 6‐item Chinese version of the Hamilton Depression Rating Scale: Mokken scaling and item analysis

Psychometric evaluation of a 6‐item Chinese version of the Hamilton Depression Rating Scale: Mokken scaling and item analysis

Residual Symptoms Related to Physical and Panic Symptoms at Baseline Predict Remission of Depression at Follow-Up

Treatment-emergent depression and anxiety between peginterferon alpha-2a versus alpha-2b plus ribavirin for chronic hepatitis C

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