Performing fatigue tests at ultrasonic frequencies, e.g. 20 000 Hz, allows one to perform experiments beyond 109 and 1010 cycles within half a day or a week, respectively. The testing technique has led to the construction of fatigue machines of high technical standard. Use of the ultrasound technique to study the mechanisms of crack initiation in pure metal single crystals, in cast alloys with voids being crack initiation sites, and in complicated fibre‐reinforced laminates is reported. Likewise, use of ultrasonic loading to study the mechanisms of crack propagation is discussed, as well as LEFM principles; especially when these principles cannot be applied. It is shown how crack growth retardation with increasing crack length is attained in fibre‐reinforced laminates by the effect of fibre bridging. Additional experimental possibilities, e.g. random loading, variation of mean load, superposition of shear loads, variation of temperature and environment, and not only axial but also torsional loading at ultrasonic frequency, and recent research results are discussed.