The cytotoxic potential for Syzygium aromaticum and Nigella sativa essential oil compared to doxorubicin against pancreatic, colonic, and cervical cancer cell lines.
Abstract:Syzygium Aromaticum (clove) and Nigella sativa (black seed), traditional medicinal herbs, display broad anticancer activity. The observations supported these oils' anti-proliferative and cytotoxic activities by MTT assay. The cold-pressed extracted oil was evaluated against cervical (HeLa), pancreatic (Panc), and colon (HCT) carcinoma cells compared to doxorubicin. Clove oil had the lowest IC 50 values against HeLa, HCT, and Panc cells, which were 0.25, 0.38, and 5.26 µg/ml, respectively. Black seed oil was ne… Show more
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