The danger of underlying<i>Chlamydia trachomatis</i>infection in treating urinary tract infection with over-the-counter antibiotics

Winceslaus, S J; Venkateshwaran, Sivaraj

doi:10.1136/bmj.h4423

Cited by 2 publications

(4 citation statements)

References 5 publications

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“…34 Although 70% of chlamydia infections are asymptomatic, some infections may lead to urethral syndrome and pelvic infection. 35 N. gonorrhoeae infection is asymptomatic in 50% of cases, and may increase the risk of premature birth four-fold. 36 Other complications include the risk of infection of sexual partners, pelvic inflammatory disease, infertility, arthritis, and spread via the bloodstream.…”

Section: Asymptomatic Bacteriuria In Pregnant Womenmentioning

confidence: 99%

“…Atypical UTIs and bacterial vaginosis in pregnancy Atypical UTIs are commonly caused by Chlamydia trachomatis (C. trachomatis) and Neisseria gonorrhoeae (N. gonorrhoeae) 34. Although 70% of chlamydia infections are asymptomatic, some infections may lead to urethral syndrome and pelvic infection 35. N. gonorrhoeae infection is asymptomatic in 50% of cases, and may increase the risk of premature birth four-fold.…”

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confidence: 99%

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Risk factors and predisposing conditions for urinary tract infection

Storme

Saucedo

García-Mora

et al. 2019

Therapeutic Advances in Urology

180

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Understanding individual and population-specific risk factors associated with recurrent urinary tract infections (UTIs) can help physicians tailor prophylactic strategies. Frequent intercourse, vulvovaginal atrophy, change of the local bacterial flora, history of UTIs during premenopause or in childhood, family history, and a nonsecretor blood type are substantiated risk factors for recurrent uncomplicated UTIs. This is a narrative review based on relevant literature according to the experience and expertise of the authors. Asymptomatic bacteriuria is generally benign; however, during pregnancy it is more common and is associated with an increased likelihood of symptomatic infection, which may harm the mother or fetus. Screening of pregnant women and appropriate treatment with antimicrobials must be balanced with the potential for adverse treatment-related outcomes; appropriate prophylaxis should be considered where possible. High-quality data are currently lacking on risks related to asymptomatic bacteriuria in pregnancy and further data in this hard-to-study population should be a primary concern for researchers. Incomplete voiding represents the primary risk factor for UTIs associated with conditions such as urinary incontinence and prolapse. Correcting the presence of residual urine remains the most effective prophylaxis in these populations. Bladder function alters throughout life; however, changes in function may be particularly profound in clinical populations at high risk of UTIs. Patients with neurogenic bladder will also likely have other evolving medical issues which increase the risk of UTIs, such as repeated catheterization and increasing residual urine volume. More aggressive antimicrobial prophylactic strategies may be appropriate in these patients. Again, the paucity of data on prophylaxis in these high-risk patients requires the attention of the research community.

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Section: Asymptomatic Bacteriuria In Pregnant Womenmentioning

confidence: 99%

mentioning

confidence: 99%

Risk factors and predisposing conditions for urinary tract infection

Storme

Saucedo

García-Mora

et al. 2019

Therapeutic Advances in Urology

180

View full text Add to dashboard Cite

show abstract

“…Currently, at least 700,000 people die each year from drug‐resistant diseases. [ 4,5 ] Japan, Australia, the European Union (EU), and China have strict regulations for quinolone residues in pork, of which Japan has the most stringent regulations; the maximum residue level in pork must not exceed 50 μg kg −1 . [ 6 ]…”

Section: Introductionmentioning

confidence: 99%

“…Currently, at least 700,000 people die each year from drug-resistant diseases. [4,5] Japan, Australia, the European Union (EU), and China have strict regulations for quinolone residues in pork, of which Japan has the most stringent regulations; the maximum residue level in pork must not exceed 50 μg kg À1 . [6] Chromatography, mass spectrometry, and chromatography-mass spectrometry are efficient and accurate methods for the detection of antibiotic residues in pork.…”

Section: Introductionmentioning

confidence: 99%

Rapid detection and whole class control of quinolone antibiotics in pork based on surface‐enhanced Raman spectroscopy

Zheng

Liu

Wen

et al. 2023

J Raman Spectroscopy

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The problem of excessive quinolone antibiotic residues in pork has stimulated great attention from the international community. However, due to the diversity and structural similarity of quinolone antibiotics, it is difficult to perform multi-residue rapid detection at the same time. Currently, antibiotic multiresidue detection methods include ultra-performance liquid chromatography (UPLC) and colloidal gold immunochromatography. However, it cannot be widely used in on-site rapid detection due to its shortcomings such as the need for high cost and low sensitivity. Herein, we report the use of surface-enhanced Raman spectroscopy (SERS) technology for the study of similar structures of quinolone antibiotics. A method for whole class control and rapid quantitative detection of all quinolone antibiotics in pork was established. By using the above method, the detection limit of single standard quinolone antibiotics was 10 μg L À1 , and the detection limit of the mixed standard was 1 μg L À1 , meeting the international requirements for the detection limit of quinolone antibiotics in pork. At last, by adding a variety of quinolone antibiotics to pork, the real detection set-up was simulated. The recovery of standard addition was 86.6%-95.3%, and the whole class control method has been well applied, which is of great significance for the detection of pork quinolone antibiotics. Compared with colloidal gold immunochromatography, our method has 2.5 times the detection speed, 1/60 times the cost, and can be quantitatively detected. The method is simple, economical, and efficient and has great application value with broad application prospects in the field of rapid detection of pork antibiotics in the future.

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The danger of underlyingChlamydia trachomatisinfection in treating urinary tract infection with over-the-counter antibiotics

Cited by 2 publications

References 5 publications

Risk factors and predisposing conditions for urinary tract infection

Risk factors and predisposing conditions for urinary tract infection

Rapid detection and whole class control of quinolone antibiotics in pork based on surface‐enhanced Raman spectroscopy

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