The Danish National Birth Cohort: Selected scientific contributions within perinatal epidemiology and future perspectives

Andersen, Anne‐Marie Nybo; Olsen, Jørn

doi:10.1177/1403494811407674

Cited by 38 publications

(40 citation statements)

References 35 publications

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“…Established risks for the fetus that relate to life circumstances and so-called lifestyle factors include smoking and second hand smoke, alcohol and other licit and nonlicit drugs, and physical exercise linked to factors such as obesity [4,5]. These might be viewed as "social environmental risk factors" where data are often extensive and research has been conducted in some instances for decades.…”

Section: Introductionmentioning

confidence: 99%

Risk Perceptions of Environmental Hazards and Human Reproduction: A Community-Based Survey

et al. 2012

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Objectives. We have investigated the Australian public's perceived risks on human reproductive health from a number of identified environmental hazards. Methods. A sample of 1261 subjects was interviewed. This interview included specific questions related to perceived risks of certain environmental hazards to human reproductive health. Results. Women were almost twice as likely to rank all hazards as harmful or very harmful to human reproduction than men. Age also influenced perceived risk with those in the 35 and older age groups more likely to rank lead as a harmful hazard when compared with the 18-34 group. Pesticides were identified by 84.5% of the sample as the most harmful environmental hazard to human reproduction. Conclusions. Similar to other environmental hazards, different groups of people in the general population perceive hazards relating to reproductive health differently. This information is important for both policy makers and health professionals dealing with reproductive environmental health issues.

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Section: Introductionmentioning

confidence: 99%

Risk Perceptions of Environmental Hazards and Human Reproduction: A Community-Based Survey

et al. 2012

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“…31,32 They were interviewed by telephone during pregnancy and when the offspring was 6 and 18 months old. The interviews were designed to study the mother’s lifestyle during pregnancy and the short- and long-term effects of this on the child, assessing a wide range of neurodevelopmental features in children but not to detect specific developmental disorders.…”

Section: Methodsmentioning

confidence: 99%

Early development in Rett syndrome – the benefits and difficulties of a birth cohort approach

Marschik

Lemcke

Einspieler

et al. 2017

Developmental Neurorehabilitation

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Purposes: Typically, early (pre-diagnostic) development in individuals later diagnosed with Rett syndrome (RTT) has been investigated retrospectively using parent reports, medical records and analysis of home videos. In recent years, prospective research designs have been increasingly applied to the investigation of early development in individuals with late phenotypical onset disorders, for example, autism spectrum disorder. Methods: In this study, data collected by the Danish National Birth Cohort lent itself to prospective exploration of the early development of RTT, in particular early motor-, speech-language, and socio-communicative behaviors, mood, and sleep. Results and Conclusions: Despite limitations, this quasi prospective methodology proved promising. In order to add substantially to the body of knowledge, however, specific questions relating to peculiarites in early development could usefully be added to future cohort studies. As this involves considerable work, it may be more realistic to consider a set of indicators which point to a number of developmental disorders rather than to one.

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“…The cohort is furthermore a result of a major grant from this Foundation. Additional support for the DNBC is obtained from the Pharmacy Foundation, the Egmont Foundation, the March of Dimes Birth Defects Foundation, the Augustinus Foundation, and the Health Foundation (Andersen & Olsen, 2011;Olsen et al, 2001).…”

Section: The Danish National Birth Cohort Study (Dnbc)mentioning

confidence: 99%

“…Written information about the cohort was provided to the women by general practitioners (GP) at the first antenatal visit, and the women enrolled in the cohort gave consent to participate in four telephone interviews, to have blood samples taken and stored in a biobank, and to have her and her offspring's data linked to routinely collected health data. Overall, the women gave consent that the data could be used for research purposes "with the aim of improving health for future children and mothers" and that they accepted to be contacted for further data collection rounds in the future (Andersen & Olsen, 2011;Olsen et al, 2001).…”

Section: Study Population/recruitmentmentioning

confidence: 99%

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Review of the state of the art of human biomonitoring for chemical substances and its application to human exposure assessment for food safety

Choi¹,

Mørck²,

Polcher³

et al. 2015

EFS3

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Human biomonitoring (HBM) measures the levels of substances in body fluids and tissues. Many countries have conducted HBM studies, yet little is known about its application towards chemical risk assessment, particularly in relation to food safety. Therefore a literature search was performed in several databases and conference proceedings for 2002 -2014. Definitions of HBM and biomarkers, HBM techniques and requirements, and the possible application to the different steps of risk assessment were described. The usefulness of HBM for exposure assessment of chemical substances from food source, and for the implementation of a systematic Post Market Monitoring (PMM) approach for regulated chemical substances was evaluated. An inventory of HBM programmes provides detailed information about study design, analytical methods, reference values (RV) and biomarkers used. Environmental monitoring and associations between HBM values and food, as well as coverage of substances and remaining deficits are highlighted. The review of study results provides information on emerging chemicals, higher exposed and particularly vulnerable populations.Conclusions: HBM can bring added value for chemical risk assessment in food safety areas (namely exposure assessment), and for the implementation of a systematic PMM approach. But further work needs to be done to improve usability. Major deficits are the lack of HBM guidance values on a considerable number of substance groups, for which health based guidance values (HBGVs) have been developed, insufficient knowledge regarding exposure sources, and incomplete dietary intake assessment. Recommendations: We recommend to foster development of HBM based guidance values and validated analytical methods/BMs, stronger inclusion of substances of interest for EFSA in European surveys, expanded monitoring of highly exposed and vulnerable subgroups, uptake of EFSA guidance concerning dietary intake assessment, as well as biobanking, surveillance synergies and targeted research, and an EU wide collaborative approach to support the future use of HBM in PMM.©BiPRO GmbH, 2015 DISCLAIMERThe present document has been produced and adopted by the bodies identified above as author(s). This task has been carried out exclusively by the author(s) in the context of a contract between the European Food Safety Authority and the author(s), awarded following a tender procedure. The present document is published complying with the transparency principle to which the Authority is subject. It may not be considered as an output adopted by the Authority. The European Food Safety Authority reserves its rights, view and position as regards the issues addressed and the conclusions reached in the present document, without prejudice to the rights of the authors. The present document has been produced and adopted by the bodies identified above as author(s). This task has been carried out exclusively by the author(s) in the context of a contract between the European Food Safety Authority and the author(s), awarded foll...

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The Danish National Birth Cohort: Selected scientific contributions within perinatal epidemiology and future perspectives

Cited by 38 publications

References 35 publications

Risk Perceptions of Environmental Hazards and Human Reproduction: A Community-Based Survey

Risk Perceptions of Environmental Hazards and Human Reproduction: A Community-Based Survey

Early development in Rett syndrome – the benefits and difficulties of a birth cohort approach

Review of the state of the art of human biomonitoring for chemical substances and its application to human exposure assessment for food safety

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