The Demographics of Molar Pregnancies in BPKIHS

Koirala, Arun Kumar; Khatiwada, Prashant; Giri, Arun; Kandel, Patricia F.; Regmi, Mohan Chandra; Upreti, D

doi:10.3126/kumj.v9i4.6349

Cited by 16 publications

(13 citation statements)

References 10 publications

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“…24,26 During the study period, 84 cases of uterine GTD were observed. The incidence of GTD in present study was 2.48 /1000 which is lower than those reported by other studies done by Jagtap et al 27 showing incidence as 4/1000, Agrawal N et al, 28 and Koiral A et al 29 showing incidence as 4.17/1000 and 3.94/1000 respectively.…”

Section: Discussioncontrasting

confidence: 70%

The frequency of hydatidiform mole in a tertiary care hospital from central India

Patil¹,

Gangane²,

Shivkumar³

2020

IJPO

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The gestational trophoblastic disease (GTD) is a group of pregnancy related tumours encompassing complete and partial mole, invasive moles, choriocarcinomas and placental site trophoblastic tumours. Amongst all GTD, hydatidiform moles are the most common form. Hydatidiform mole is a relatively common gynecological condition which could presents like spontaneous abortion, one of the most common gynecological emergencies. Materials and Methods: Present study is a retrospective analysis to determine incidence of hydatidiform mole for eight years duration.All women who were diagnosed of molar pregnancy by estimation of beta hCG and histopathological examination during1st Jan 2010 to 31st Dec 2017 were enrolled in this study. During the study period, there were 84 cases of Molar pregnancy out of 33856 total deliveries. Results: The total number of deliveries reported in the study period was 33856 out of which 84 cases were of gestational trophoblastic disease (GTD). The prevalence of GTD in this tertiary care hospital was 2.48 per 1000 deliveries. During the study period, we had received 55 samples of products of conception and 3079 hysterectomy specimens. Out of 3134 cases, 84 cases were diagnosed as GTD. Out of these 84 cases 81cases were hydatidiform mole. There were two cases of choriocarcinomas and one case of placental site trophoblastic tumour. Conclusion: The prevalence of hydatidiform mole was higher among all entities of gestational trophoblastic disease. The serum beta hCG levels are very sensitive and specific for diagnosis. Histopathological examination is helpful for confirming diagnosis.

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Section: Discussioncontrasting

confidence: 70%

The frequency of hydatidiform mole in a tertiary care hospital from central India

Patil¹,

Gangane²,

Shivkumar³

2020

IJPO

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“…Age less than 20 years is not considered as a risk factor by WHO, though some experts have observed both extremes (<20 years and >35 years) to be at increased risk of disease. [12][13][14][15] In the present study the commonest symptom after amenorrhea is per vaginum bleeding, seen in 68.2% of patients. The clinical study from Dubai reported incidence of vaginal bleeding in 29% patients only.…”

Section: Discussionsupporting

confidence: 52%

Clinical study of gestational trophoblastic disease in a tertiary care hospital

Mulik

Choudhary

2020

Int J Reprod Contracept Obstet Gynecol

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Background: Gestational trophoblastic diseases (GTDs) had been associated with significant morbidity and mortality till recently. Wide variation in incidences have been reported worldwide. The present study was planned with the objective of determination of incidence, assessment of risk factors, clinical presentation, management protocols and outcomes in GTD cases in Indian population at a tertiary care centre.Methods: All the diagnosed cases of GTD reporting to study centre during study period of 1.5 years were included. Detailed history taking, examination and relevant investigations (Hb%, blood grouping, thyroid functions, serum ß-hCG, USG and chest X-ray) were undertaken. Suction and evacuation were done for all patients as primary mode of management and samples were sent for histopathological examination. Comprehensive follow ups were done, including weekly ß-hCG until normal for 3 consecutive weeks followed by monthly determination until the levels were normal for 6 consecutive months.Results: Total 22 cases out of 19500 deliveries were diagnosed as GTD (incidence rate-1.13/1000 deliveries). Mean age was 23.64±3.89 years with 50% participants being primigravida. The commonest symptom after amenorrhea 22 (100%) was bleeding per-vaginum 15 (68.2%). Maximum cases were of complete hydatidiform mole histopathology 16 (72.73%), USG 19 (86.4%). Clinical characteristics were statistically comparable between patients of complete mole and partial mole. Out of 22 cases, 1 (4.5%) was diagnosed as GTN.Conclusions: Early diagnosis and treatment along with regular follow up is the key in GTD. There is need to establish a centralized disease specific registry in future.

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“…7,9,10 Like in this study, the incidence of choriocarcinoma was less (0.33-4.3%) in other studies. 6,8,11,24,25 This is in FRQWUDVW WR WKH ¿QGLQJ RI VWXG\ GRQH E\ Mohammad et al 7 in Nigeria where choriocarcinoma was the commonest cancer of corpus uteri.…”

Section: (Qgrphwuldo Fdqfhu Dqg Fkrulrfduflqrpdmentioning

confidence: 99%

Malignant Tumors of the Female Genital Tract – a Hospital Based Analysis

Joshi

Baral

Malla

2016

Nepal j. obstet. gynaecol.

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were included in the study.Results: Among 62 cases, cervical cancer was the commonest (71%) followed by ovarian cancer (14%), endometrial FDQFHU DQG FKRULRFDUFLQRPD 0DMRULW\ RI ZRPHQ EHORQJHG WR \HDUV IRU HDFK W\SH RI WXPRUV )RXU¿IWK RI endometrial, half of the cervical and one-third of ovarian cancers were among grand-multipara. Sixty nine percent of women received treatment with 22 (9 cervical, 9 ovarian, 3 endometrial and one of corpus uteri) surgical and 21 primary chemo/ radiotherapy but 19 (31%) were lost for follow-up. Squamous type of cervical cancer was the commonest (93%). Conclusions:Cervical cancer was the commonest genital tract malignancy followed by ovarian cancer, endometrial cancer and choriocarcinoma. For each type of tumors, 50-59 years was the common age group and grand multiparity was seen in half of the women with the cervical cancer. Squamous type of cervical cancer was the commonest variety..H\ZRUGV genital; malignancy; tumor.

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The Demographics of Molar Pregnancies in BPKIHS

Cited by 16 publications

References 10 publications

The frequency of hydatidiform mole in a tertiary care hospital from central India

The frequency of hydatidiform mole in a tertiary care hospital from central India

Clinical study of gestational trophoblastic disease in a tertiary care hospital

Malignant Tumors of the Female Genital Tract – a Hospital Based Analysis

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