Rangkui River is a river that passes through the area of Pangkalpinang City, Indonesia. The condition of the River Rangkui is now polluted, especially in the urban areas. Utilization of water quality model is one popular method to recover the river condition. Deoxygenation rate is an important coefficient in the BOD-DO formula used in the water quality model. This study was aimed to find out the actual coefficient of water deoxygenation rate of Rangkui River, especially in the dry season. Sampling was conducted at two location points that are considered to represent the condition of rivers in urban areas. The method of laboratory analysis used in the calculation of deoxygenation rate was using Winkler Method and Slope Method, while empirical formula used in deoxygenation rate calculation was using Hydroscience Equation formula for normal flow. The results showed that the value of deoxygenation rate range (K1) in the Rangkui River was between 0.14 to 0.41 per day and the BOD Ultimate (La) range was between 8.53 to 70.64 mg / L. As for the value of deoxygenation rate range (K1) on the River Rangkui using empirical formula was ranging from 0.49 to 0.55 per day. Higher values of deoxygenation rate generated from the empirical formula show the characteristic of typical polluted urban rivers.