Fibre-reinforced polymer composites are increasingly used to make pipes and pressure vessels. The relationship between wet-winding manufacturing, composite microstructure, and the mechanical performance is complex due to many process parameters and material properties involved. Efficient manufacturing aspirations however drive process innovations that include new, radically different tow impregnation methods. In this work, the process–property–performance relationship is experimentally construed for hoop-wound carbon fibre/epoxy composite cylinders. The difference between cylinders produced by a new tow impregnation system and cylinders from the reference impregnation system was investigated. Winding speed and cylinder wall thickness were considered as two additional variables. The results indicate that, within current scope, composite microstructure is relatively insensitive to the winding speed and to final cylinder thickness. Meanwhile, un-optimized changes for tow impregnation affect the void content, the size distribution of voids and the interlaminar failure mode in short beam shear.