The design strategy of intelligent biomedical magnesium with controlled-release platform

Bi, Yanze; Zhu, Xinyun; Zhao, Jian‐Liang; Cui, Hanrui; Wang, Zhenguo; Li, Yan; Wang, Caiqi

doi:10.1016/j.msec.2018.12.031

Cited by 7 publications

(2 citation statements)

References 52 publications

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“…Notably, the catecholamine moieties of PDA coating can interact with Ca 2+ ions, and thus promote biomimetic mineralization of hydroxyapatite (HA) ( Ghorbani et al, 2019 ). Furthermore, when applied on biodegradable materials, the PDA coating can help improve corrosion resistance ( Bi et al, 2019 ).…”

Section: Formation and Function Of Pda Coatingmentioning

confidence: 99%

Mussel-Inspired Polydopamine-Based Multilayered Coatings for Enhanced Bone Formation

Zhao

Lin

et al. 2022

Front. Bioeng. Biotechnol.

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Repairing bone defects remains a challenge in clinical practice and the application of artificial scaffolds can enhance local bone formation, but the function of unmodified scaffolds is limited. Considering different application scenarios, the scaffolds should be multifunctionalized to meet specific demands. Inspired by the superior adhesive property of mussels, polydopamine (PDA) has attracted extensive attention due to its universal capacity to assemble on all biomaterials and promote further adsorption of multiple external components to form PDA-based multilayered coatings with multifunctional property, which can induce synergistic enhancement of new bone formation, such as immunomodulation, angiogenesis, antibiosis and antitumor property. This review will summarize mussel-inspired PDA-based multilayered coatings for enhanced bone formation, including formation mechanism and biofunction of PDA coating, as well as different functional components. The synergistic enhancement of multiple functions for better bone formation will also be discussed. This review will inspire the design and fabrication of PDA-based multilayered coatings for different application scenarios and promote deeper understanding of their effect on bone formation, but more efforts should be made to achieve clinical translation. On this basis, we present a critical conclusion, and forecast the prospects of PDA-based multilayered coatings for bone regeneration.

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Section: Formation and Function Of Pda Coatingmentioning

confidence: 99%

Mussel-Inspired Polydopamine-Based Multilayered Coatings for Enhanced Bone Formation

Zhao

Lin

et al. 2022

Front. Bioeng. Biotechnol.

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“…The science uses these intrinsic sensitive properties of the smart materials to tune and develop the desired response to a specific stimulus, creating very functional devices and systems, demanded in various areas with different applications. The research and development of these smart systems have allowed technological advances to a wide range of applications, like drug delivery systems, , biosensors, , water treatment devices, energy generation and storage, aeronautical industry, and anticorrosion coatings. ,,− …”

Section: Introductionmentioning

confidence: 99%

Zinc-Layered Hydroxide Salt Intercalated with Molybdate Anions as a New Smart Nanocontainer for Active Corrosion Protection of Carbon Steel

Leal

Marino

2020

ACS Appl. Mater. Interfaces

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The use of smart nanocontainers to store corrosion inhibitors in coatings significantly increases the efficiency and durability of the coating, providing active corrosion protection.Here we report the synthesis of a zinc-layered hydroxide salt (LHS) and its use as a novel nanocontainer for this purpose, storing the corrosion inhibitor molybdate in the interlayer region of the LHS. Layered zinc hydroxide molybdate (ZHM) was obtained by anion-exchange reactions using layered zinc hydroxide acetate (ZHA) as a precursor, obtained by alkaline coprecipitation. The release behavior of molybdate from the ZHM nanocontainers in aqueous NaCl solution (0.05 mol/L) was evaluated using UV− vis absorption spectroscopy. The molybdate release from the ZHM nanocontainers was realized by the anion-exchange mechanism, where chloride anions replaced intercalated molybdate anions. The release was fast in the first minutes of exposure, followed by a controlled release afterward, reaching about 35% of cumulative amount of released molybdate after 30 days of exposure. The anticorrosion effect provided by the ZHM nanocontainers for carbon steel was investigated by electrochemical impedance spectroscopy. The steel substrate was coated with an epoxy resin loaded with ZHM nanocontainers (5 wt %) and immersed in an NaCl solution (0.05 mol/L) to evaluate the active mechanisms of inhibition and the anticorrosion properties of the loaded coating in comparison with a neat coating (blank). The coating loaded with ZHM nanocontainers presented the best corrosion protection performance, exhibiting an increase of R C (coating resistance) with the immersion time and superior R P (polarization resistance) for all the measured periods, compared to the blank. This effect is a consequence of the double mechanism of protection provided by the ZHM nanocontainers: (i) stimulus-response release of molybdate and its active inhibition in the scratched region by the formation of an insoluble protective film, simultaneously with (ii) removal of the corrosive chloride species from the medium.

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Enhancement of the adhesion and anticorrosive properties of an epoxy coating by the application of a cerium based film

Loperena

Lehr²,

Saidman³

2022

International Journal of Adhesion and Adhesives

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The design strategy of intelligent biomedical magnesium with controlled-release platform

Cited by 7 publications

References 52 publications

Mussel-Inspired Polydopamine-Based Multilayered Coatings for Enhanced Bone Formation

Mussel-Inspired Polydopamine-Based Multilayered Coatings for Enhanced Bone Formation

Zinc-Layered Hydroxide Salt Intercalated with Molybdate Anions as a New Smart Nanocontainer for Active Corrosion Protection of Carbon Steel

Enhancement of the adhesion and anticorrosive properties of an epoxy coating by the application of a cerium based film

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