The DESIR cohort: A 10-year follow-up of early inflammatory back pain in France: Study design and baseline characteristics of the 708 recruited patients

Dougados, Maxime; D’Agostino, Maria-Antonietta; Bénessiano, Joëlle; Bérenbaum, Francis; Bréban, Maxime; Claudepierre, Pascal; Combe, Bernard; Dargent-Molina, Patricia; Daurès, Jean‐Pierre; Fautrel, Bruno; Feydy, A.; Goupille, Philippe; Leblanc, Véronique; Logeart, I.; Pham, Thao; Richette, Pascal; Roux, Christian; Rudwaleit, Martín; Saraux, Alain; Tréluyer, Jean‐Marc; Heijde, Desirée van der; Wendling, Daniel

doi:10.1016/j.jbspin.2011.01.013

Cited by 211 publications

(150 citation statements)

References 30 publications

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“…The French Society of Rheumatology has recently initiated a huge national multicenter cohort, the so-called "DESIR cohort study" (Devenir des spondyloarthrites indifférenciées récentes [DESIR]) to facilitate investigations on diagnostic and prognostic markers but also aetiologic, pathogenic and socio-economic factors among patients with early inflammatory back pain suggestive of axial spondyloarthritis [15].…”

Section: Introductionmentioning

confidence: 99%

Clinical presentation of patients suffering from recent onset chronic inflammatory back pain suggestive of spondyloarthritis: The DESIR cohort

et al. 2015

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Section: Introductionmentioning

confidence: 99%

Clinical presentation of patients suffering from recent onset chronic inflammatory back pain suggestive of spondyloarthritis: The DESIR cohort

et al. 2015

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“…Data from eight studies performed in patients with suspected axSpA with a wide range of symptom duration (<2 to >7 years) indicates that the proportion of nr-axSpA patients among those with newly diagnosed axSpA is between 23-80 % [8,[11][12][13][14][15][16][17][18]. The wide variation may be due to differences in symptom duration and other parameters such as interpretation of MRI results [12].…”

Section: Natural History Of Nonradiographic Axial Spamentioning

confidence: 99%

Nonradiographic axial spondyloarthritis background and confounding factors of this new terminology: an appraisal

Erbil

Espinoza

2014

Clin Rheumatol

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The advent of biologic therapy in the treatment of rheumatic diseases has intensified the need to further define and characterize spondyloarthritis (SpA). There has been a long debate over nomenclature of the SpA subtypes. There are those who are considered "lumpers," favoring the notion that different entities of the SpA groups are manifestations of the same disease, and "splitters," those who believe the different SpA groups represent separate diseases with shared clinical features. The influential work by Moll et al. has led to separation of entities and recognition of etiological processes of SpA subtypes. Among these subtypes has emerged nonradiographic axial spondyloarthritis (nr-axSpA), which is believed to be either an early form of ankylosing spondylitis (AS) or perhaps a different disease entity altogether. Recently attention has shifted to the characterization of early SpA, with special emphasis on nonradiographic axial SpA. The Assessment of Spondyloarthritis International Society (ASAS) has developed new criteria for the classification of this disease entity. Along with the advent of these criteria have come several unanswered questions. Although data suggests that nr-axSpA will evolve into AS over time, the natural evolution of disease is still undetermined since a proportion of cases do not progress. A number of questions also remain regarding features of patients with AS compared to those with nonradiographic disease. This appraisal highlights the differences in disease characteristics between men and women in regards to measures of disease activity, inflammatory markers, and radiologic findings. Recent studies also suggest fibromyalgia as a potential confounding factor in assessing disease activity and establishing a diagnosis of axSpA in the female population. Nonradiographic axial SpA is a relevant disease subgroup of axial SpA, and several questions have been left unanswered with more research needed regarding diagnosis (particularly in women), treatment, and long-term disease course.

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“…At each visit, any treatment modifications such as TNF␣ antagonist initiation were recorded (10). The outcome measure for our study was TNF␣ antagonist initiation within 6 or 12 months after inclusion.…”

Section: Followup and Outcomementioning

confidence: 99%

Early Tumor Necrosis Factor α Antagonist Therapy in Everyday Practice for Inflammatory Back Pain Suggesting Axial Spondyloarthritis: Results From a Prospective Multicenter French Cohort

Canouï‐Poitrine

Poulain

Moltó

et al. 2014

Arthritis Care & Research

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The DESIR cohort: A 10-year follow-up of early inflammatory back pain in France: Study design and baseline characteristics of the 708 recruited patients

Cited by 211 publications

References 30 publications

Clinical presentation of patients suffering from recent onset chronic inflammatory back pain suggestive of spondyloarthritis: The DESIR cohort

Clinical presentation of patients suffering from recent onset chronic inflammatory back pain suggestive of spondyloarthritis: The DESIR cohort

Nonradiographic axial spondyloarthritis background and confounding factors of this new terminology: an appraisal

Early Tumor Necrosis Factor α Antagonist Therapy in Everyday Practice for Inflammatory Back Pain Suggesting Axial Spondyloarthritis: Results From a Prospective Multicenter French Cohort

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