The Determination of 4-Aminoquinoline Antimalarials: Revaluation of the Induced Fluorescence Method, with Specific Application to Hydroxychloroquine Analysis*

McChesney, Evan W.; Wyzan, Henry S.; McAuliff, John P.

doi:10.1002/jps.3030450917

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Chemotherapeutics1

In Vivo Experiments1

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1959

2019

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Cited by 23 publications

(2 citation statements)

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“…Polarography, voltametry, and amperometry have been applied to the determination of some of the synthetic antimalarials (261). A simplification of the induced fluorescence method of Brodie and others for the determination of 4-aminoquinoline antimalarials has been reported (393).…”

Section: Chemotherapeuticsmentioning

confidence: 99%

Pharmaceuticals

Slack¹,

Mader²

1959

Anal. Chem.

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Section: Chemotherapeuticsmentioning

confidence: 99%

Pharmaceuticals

Slack¹,

Mader²

1959

Anal. Chem.

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“…Determination of hydroxychloroquine sulfate concentration in plasma was done ac cording to McChesney et al (18).…”

Section: In Vivo Experimentsmentioning

confidence: 99%

Clinical and Experimental Evaluation of the Thromboprophylactic Effect of Hydroxychloroquine Sulfate after Total Hip Replacement

Johansson¹,

Forsberg²,

Johnsson³

1981

Pathophysiol Haemos Thromb

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The rate of postoperative deep vein thrombosis was studied by the ¹²⁵I-fibrinogen method in 35 patients after total hip replacement. 12 out of 18 patients treated prophylactically with hydroxychloroquine sulfate developed deep vein thrombosis compared with 11 out of 17 patients in the control group. Platelet aggregability was inhibited in vitro by high concentrations of hydroxychloroquine sulfate, but these concentrations were not obtained in vivo and platelet aggregation was not inhibited in patients treated with hydroxychloroquine sulfate (Plaquenil®).

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Pharmacology of Antimalarial Drugs, Current Anti-malarials

Na‐Bangchang¹,

Karbwang²

2019

Encyclopedia of Malaria

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Currently available antimalarial drugs can be classified into four broad categories according to their chemical structures and modes of action. 1. Arylamino alcohol compounds: quinine, quinidine, chloroquine, amodiaquine, mefloquine, halofantrine, piperaquine, and lumefantrine 2. 8-Aminoquinoline: primaquine and tafenoquine 3. Antifolate compounds: sulfadoxine, pyrimethamine, proguanil, chlorproguanil, and trimethoprim 4. Artemisinin compounds: artemisinin, artesunate, artemether, b-arteether, and dihydroartemisinin 5. Others: atovaquoneand antibacterial drugs (tetracycline, doxycycline, and clindamycin) Arylamino Alcohol Antimalarials Chloroquine Chloroquine was first synthesized by Bayer in Germany as early as 1934. The initial clinical

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The Determination of 4-Aminoquinoline Antimalarials: Revaluation of the Induced Fluorescence Method, with Specific Application to Hydroxychloroquine Analysis*

Cited by 23 publications

References 6 publications

Pharmaceuticals

Pharmaceuticals

Clinical and Experimental Evaluation of the Thromboprophylactic Effect of Hydroxychloroquine Sulfate after Total Hip Replacement

Pharmacology of Antimalarial Drugs, Current Anti-malarials

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