The Determination of Benzo[a]Pyrene and Benz[a]Anthracene in Mainstream and Sidestream Smoke of the Kentucky Reference Cigarette 1R4F and a Cigarette Which Heats but Does Not Burn Tobacco: A Comparison

Chromatography, Absorption, and Fluorescence: A New Instrumental Analysis Experiment on the Measurement of Polycyclic Aromatic Hydrocarbons in Cigarette Smoke

“…For example, environmental tobacco smoke particles from Kentucky Reference 1R4F cigarettes were reported to contain 412 ± 36 ng of chrysene and 152 ± 23 ng of benzo[a]anthracene per cigarette (10), values similar to those reported here for an unfiltered commercial cigarette. In another study, side-stream smoke collected from a Kentucky Reference cigarette 1R4F on filter pads and analyzed by HPLC gave 219 ng of benzo[a]anthracene per cigarette (11). Chrysene in cigarette smoke condensate, which was isolated by cold trap and liquid-liquid extractions followed by several chromatographic separations, was reported to be 70 ng per cigarette (12), a factor of 10 less than that found in this experiment.…”

Doses of Nicotine and Lung Carcinogens Delivered to Cigarette Smokers

“…The mainstream smoke generated via the smoking machine programmed with topographic smoking parameters from individual study participants was analyzed for tar, nicotine, carbon monoxide, BaP, and NNK, as described elsewhere (35)(36)(37)(38)(39)(40)(41)(42)(43)(44)(45). Each compound of interest was assayed in triplicate in the smoke collected from the smoking of four cigarettes under parameters obtained for each participant studied.…”

Determination of Polycyclic Aromatic Hydrocarbons In Exhaled Cigarette Smoke

“…For the analysis, a sensitive and accurate analytical technique was necessary. A considerable number of analytical techniques are reported in the literature for the quantitation of PAHs in particulate phase of cigarette smoke (19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29). These include procedures for sample preparation such as solvent extraction, solid phase extraction (SPE), simultaneous distillation and extraction (SDE), etc.…”