The determination of oxalate in urine and urinary calculi by a new ion-chromatographic technique

Robertson, William; Scurr, D. S.; Smith, Arthur D.; Orwell, R.L.

doi:10.1016/0009-8981(82)90364-3

Cited by 53 publications

(12 citation statements)

References 17 publications

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“…The procedure was a modified version of a previously described method (7). The procedure was a modified version of a previously described method (7).…”

Section: Ion Chromatographymentioning

confidence: 99%

Determination of Oxalate Excretion in Spot Urines of Healthy Children by Ion Chromatography

Schnakenburg

Byrd²,

Latta³

et al. 1994

Clinical Chemistry and Laboratory Medicine

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Evidence for the suitability of Spot urines for selective screening in children was obtained by comparing the 24-hour urinary oxalate excretion with the ratio of urinary oxalate to creatinine [mmol/mol] in spontaneously voided urine samples. Spot urines of 169 healthy children aged l day to 13 years were analysed in order to establish reference values for the urinary oxalate/creatinine ratio in relation to age and body surface area. Oxalate was measured by automated ion chroraatography. Results showed an inverse relationship between the oxalate/creatinine ratio and age. The highest ratios, 131 ± 57 mmol/mol (mean ± 2 SD), were found in infants. At age two years, the ratio was 84 ± 55, at age five years 56 ± 35, and for children older than ten years 42 ± 31. This finding can be explained by the gain of muscle mass and hence increased creatinine productiori with increasing age. Data for the urinary oxalate/creatinine ratio are presented according to body surface area for the assessment of children with abnormal growth. In 19 urine samples from nine patients with primary hyperoxaluria, the oxalate/creatinine ratio greatly exceeded (286-2022 mmol/mol) the above reference ranges. We therefore propose the determination of the oxalate/creatinine ratio in spot urines for the selective screening for hyperoxaluria in children with nephrocalcinosis or urolithiasis.

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“…The procedure was a modified version of a previously described method (7). The procedure was a modified version of a previously described method (7).…”

Section: Ion Chromatographymentioning

confidence: 99%

Determination of Oxalate Excretion in Spot Urines of Healthy Children by Ion Chromatography

Schnakenburg

Byrd²,

Latta³

et al. 1994

Clinical Chemistry and Laboratory Medicine

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“…Urine samples were analysed as previously described (Camusso & Polesello, 2000;Gimblet et al, 1967;Moellering & Gruber, 1966;Robertson et al, 1982) for pH, creatinine, sodium, potassium, calcium, magnesium, uric acid, sulfate, phosphorus, oxalate, chloride, hippuric acid, citrate, and ammonium contents.…”

Section: Urinary Parametersmentioning

confidence: 99%

Hippuric acid in 24 h urine collections as a biomarker of fruits and vegetables intake in kidney stone formers

Guerra

Folesani

Mena

et al. 2014

International Journal of Food Sciences and Nutrition

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This work aimed to underline the prospects of hippuric acid, a product of the metabolism of polyphenols, as a new biomarker of fruits and vegetables intake associated with lithogenic risk. Biochemical parameters of lithogenic risk and hippuric acid were measured in the 24 h urine collections of a cohort of 696 Italian kidney stone formers divided into two subgroups according to their different dietary habits. The link between lithogenic risk parameters and hippuric acid was assessed and this compound was revealed as a valuable biomarker of fruits and vegetables intake in kidney stone formers. A cut-off value of urinary excretion of hippuric acid, 300 mg/24 h, was set as the threshold of discrimination between low and high intake of fruits and vegetables for these patients. These results highlight the importance of monitoring of the excretion hippuric acid in urine to address proper dietary guidelines for the management of stone former patients.

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“…Initially this technique was used for oxalic acid in urine, after only dilution with water and filtering 205 . Sulphate present in urine eluted close to oxalic acid and sulphate therefore had to be added to the aqueous standards used for preparation of the calibration curve in order to overcome the potential problem of peak overlap.…”

Section: Liquid Chromatographymentioning

confidence: 99%

Liquid chromatography–tandem mass spectrometry method for routine measurement of oxalic acid in human plasma

Elgstøen

2008

Journal of Chromatography B

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The determination of oxalate in urine and urinary calculi by a new ion-chromatographic technique

Cited by 53 publications

References 17 publications

Determination of Oxalate Excretion in Spot Urines of Healthy Children by Ion Chromatography

Determination of Oxalate Excretion in Spot Urines of Healthy Children by Ion Chromatography

Hippuric acid in 24 h urine collections as a biomarker of fruits and vegetables intake in kidney stone formers

Liquid chromatography–tandem mass spectrometry method for routine measurement of oxalic acid in human plasma

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